体外冲击波对肾脏生物学效应的实验研究  

An experimental study of biological effects of extracorporeal shock wave on kidney

作　　者：夏同礼[1] 梁丽莉[1] 孔祥田[1] 蔡碧娟[1] 郭应禄[1] 

机构地区：[1]北京医科大学泌尿外科研究所

出　　处：《中华泌尿外科杂志》1994年第4期292-294,共3页Chinese Journal of Urology

摘　　要：雄性家兔４５只，分为３组，分别接受三个能量级（２０ｋＶ，７５０ＳＷ；１４ｋＶ，１５００ＳＷ；１０ｋＶ，３０００ＳＷ）体外冲击波处理。结果表明，２组动物急性肾损伤程度较其它两组病变轻微。体外冲击波对肾脏的生物学效应表现为尿酶γＧＴ升高；超微结构显示肾小管上皮细胞变性坏死；组织学显示肾内和肾周出血。实验第２８天的生物学效应表现为吸收和（或）纤维化修复。体外冲击波能量（包括电压和冲击次数）与其对肾脏生物学效应程度相关。male rabbits were divided into three groups and were treated with three energy levels (20KV, 750SW; 14kv,1 500kv; 10kv, 3 000kv) of extracorporeal shock wave (ESW) respectively. The results suggest that acuterenal injury was minimal in the Ⅱ group as compared with the other two groups.The biological effects of ESW on kidney caused an increase of γGT in urine,degeneration and or necrosis of tubular cells in ultrastructure, and intrarenal and perirenal bleeding in histology.The biological effects were renovated with absorbtion and or fibrosis in 28 days after ESW. There was a noted relationship between the energy level (generator voltage and shock wave number) and the biological effect on kidney.

关 键 词：体外震波碎石 肾脏 生物学效应 

分 类 号：R691.4[医药卫生—泌尿科学]