生育和不育男性精液SOD活性的研究  

Superoxide dismutase activity in semen of fertile and infertile men

作　　者：陈国千[1] 陆永绥[1] 

机构地区：[1]温州医学院附属第一医院

出　　处：《中华泌尿外科杂志》1994年第4期290-291,共2页Chinese Journal of Urology

摘　　要：测定１３７例生育，２４５例不育男性的精子和精浆超氧化物歧化酶（ＳＯＤ）活性。结果不育组精子ＳＯＤ活性（１０３±３９Ｕ／１０￣９精子）显著性低于生育组（１４４±３７Ｕ／１０￣９精子），但精浆ＳＯＤ活性两组间无显著性差异。经相关分析，精子ＳＯＤ活性与精子活动率、精子正常形态及精子尾部低渗肿胀率间均呈显著性正相关；而精浆ＳＯＤ活性与上述三参数、精子密度及精子ＳＯＤ活性间均无显著相关性。提示精子ＳＯＤ活性与精子结构、功能有关，可作为衡量精液质量的一个新指标。Superoxide dismutase (SOD) activities in spermatozoa and seminal plasma of 137 fertile and 245 infertile men were measured. The results showed that spermatozoal SOD activity in infertile group (103±39 U/10￣9cells), was significantly lower than that in fertile group (144±37 U/109 cells), but no significant difference was observed in seminal plasma SOD activity between the groups. Spermatozoal SOD activity was positively correlated to sperm motility, normal morphology and sperm swelling (by sperm hypo-osmotic swelling test). There were no significant correlation between seminal plasma SOD activity and the above three parameters, the sperm density and the spermatozoal SOD activity. These results indicate that there is a close relationship between spermatozoal SOD and spermatozoal structure and function, suggesting spermatozoal SOD activity may be used as an index for the assessment of semen quality.

关 键 词：生育力 精子 超氧物歧化酶 

分 类 号：R698.202[医药卫生—泌尿科学]