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作 者:李雪芹[1] 王蕾梅[1] 廉德花[1] 徐成文[1] 朱先荣[1]
出 处:《山东医药》2003年第20期13-15,共3页Shandong Medical Journal
摘 要:目的 提高急性有机磷中毒患者的抢救成功率。方法 将 194例急性有机磷中毒患者随机分为观察组与对照组。在综合抢救治疗的基础上 ,观察组 98例患者施行洗胃后留置胃管 ,根据中毒程度分别于第 1个2 4小时和第 2个 2 4小时少量多次洗胃并灌入导泻剂 ;对照组 96例患者按传统的洗胃方法洗胃 ,洗胃后不留置胃管。观察比较两组抢救治疗效果。结果 观察组血胆碱酯酶活性显著高于对照组 ( P<0 .0 1) ;阿托品用量显著低于对照组 ( P<0 .0 1) ;并发症发生率、病死率显著低于对照组 ( P均 <0 .0 5) ;住院时间及治疗费用显著低于对照组 ( P均 <0 .0 1)。结论 洗胃后留置胃管可以及时清除胃内残留毒物 ,减少机体对毒物的重吸收 ,降低并发症发生率 。Objective Objective [WT5”BZ]To enhance the sccessful rate of patients with acute organophosphate poisoning.Methods 194 cases of organophosphate poisoning were randomely devided into the study group (98 cases)and the control group(96 cases) on the base of general therapy.The patients in the study group had the gastric tube remained after salvaging,and according to the degree of toxication,gastric lavage were performed frequently in small volume in the first and the second 24 hours,respectively.After each lavage the cathafrtics were given.The control group had conventional gastric salvage without gastric tube remained.Results The cholinestrease activation of the second group was higher than that of the control group.The cumulative dose of atropine of the study group was more lower than that of the control group.The incidences of complication,mortolity of the study group were more lower than that of the control group.In study group the time of hospitaliza tion and the costs for therapy were lower than that of the control group.Conclusion The gastric tube remained after salvaging can clear away the residual toxin in time,reduce the toxin reabsorption and complication,thereby enhance the successful rate.
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