蝉翼藤根中的一个新二苯酮  

A new benzophenone from the root of Securidaca inappendiculata

作　　者：张丽杰[1] 张琳[1] 徐丽珍[1] 杨学东[1] 邹忠梅[1] 杨世林[1] 

机构地区：[1]中国医学科学院,中国协和医科大学药用植物研究所,北京100094

出　　处：《药学学报》2005年第6期536-538,共3页Acta Pharmaceutica Sinica

摘　　要：目的　对蝉翼藤(SecuridacainappendiculataHassk. )根的二苯酮成分进行分离和结构鉴定。方法　通过硅胶和凝胶反复柱色谱分离得到二苯酮类化合物;利用多种波谱技术鉴定其化学结构。结果　分离鉴定了2个二苯酮化合物,其结构分别为2 甲氧基- 3, 4 -亚甲二氧基-二苯酮(I), 4 羟基-2, 6 -二甲氧基-二苯酮(II)。结论　化合物I为新化合物,命名为蝉翼藤二苯酮B;化合物II为首次自该属植物中分离得到。Aim To study the benzophenones in the roots of Securidaca inappendiculata Hassk.. Methods Column chromatography (including silica gel and Sephadex LH-20) was used to isolate benzophenones whose structures were elucidated by HREI-MS, NMR (1D and 2D) methods. Results A new benzophenone was isolated and identified as 2-methoxy-3,4-methylenedioxy-benzophenone (I), along with a known compound 4-hydroxy-2,6-dimethoxy-benzophenone (II). Conclusion Compound I is a new one named as securiphenone B, compound II was isolated from the genus for the first time.

关 键 词：蝉翼藤 二苯酮 蝉翼藤二苯酮B 

分 类 号：R284.1[医药卫生—中药学] R284.2[医药卫生—中医学]