核素心血池显像评价COPD并发肺心病有室功能  

A STUDY ON THE RADIONUCLDE METHOD FOR ASSESSMENT OF RIGHT VENTRICULAR FUNCION IN COPD PATIENTS WITH COR PULMONALE

作　　者：汤兵祥 张庆宪[1] 孙培宗[1] 吴嵩炜[1] 王书钧[1] 盖飞月[1] 许秀芳[1] 钟秀梅[1] 孙秉奇[1] 

机构地区：[1]河南省肺科医院内科,河南医科大学一附院呼吸内科,河南医科大学核医学科

出　　处：《中华内科杂志》1994年第11期770-772,共3页Chinese Journal of Internal Medicine

摘　　要：对１５例慢性阻塞性肺疾病（ＣＯＰＤ）并发肺心病患者进行核素心血池显像检查，并与右心导管测压作对照。结果显示：肺心病伴肺动脉高压组的右室射血分数（ＲＶＥＦ）较正常对照组和肺心病伴肺动脉压正常组均明显降低（Ｐ＜０．００１，Ｐ＜０．００１），右房舒张早期排空率（ＲＡＥＲ）和右室峰充盈率（ＲＶＰＦＲ）呈阶梯样降低，且ＲＡＥＲ和ＲＶＰＦＲ的下降出现在ＲＶＥＦ下降之前。提示右室舒张功能可能先于收缩功能受损。Right ventricular ejection fraction (RVEF)、 right ventricular peak filling rate(RVPFR)and right atrial early diastolic emptying rate(RAER)were measured with radionuclide gated blood pool scintigraphy in 19 healthy subjects and 15 cases of COPD with cor pulmonale and right heart catheterization was per-formed in the latter group.It was shown that RVEF in the group of cor pulmonale patients with pul-monary arterial hypertension (PAH)was significantly lower than that of the group of healthy suUects and cor pulmonale patients witliout PAH(P<0. 001, P<0. 001),no difference in RVEF was found between cor pulmonale patients without PAH and heaIthy suUects.As pulmonary arterial pressure increased,RAER and RVPFR decreased gradully. and the reduction of RAER and RVPFR occurred earlier than that of RVEF,It is suggested that right ventricular diastolic function may be impaired before right ventricular svstolic function.

关 键 词：肺心病 肺疾病 阻塞性 放射性核素成像 

分 类 号：R816.2[医药卫生—放射医学] R542.504[医药卫生—临床医学]