射频电磁波与环境温度对单个活态红细胞膜力学性质的影响  

Effects of radio-frequency electromagnetic wave and environmental temperature on membrane mechanical properties of single living intact human red blood cell

作　　者：姚成灿[1] 姚平[2] 唐国汉[3] 郑青[1] 李校坤[1] 黄耀熊[4] 

机构地区：[1]暨南大学药学院,广东广州510630 [2]暨南大学医学院生理教研室,510630 [3]广东省职业病防治院,510300 [4]暨南大学生物医学工程研究所,510630

出　　处：《中国职业医学》2005年第3期11-13,共3页China Occupational Medicine

基　　金：广东省自然科学基金重点项目(010420);暨南大学引进人才启动基金资助项目

摘　　要：目的探讨900MHz射频电磁波和环境温度对红细胞膜力学性质的协同作用。方法利用多维显微成像技术和显微动态图像分析技术,观察和测量不同温度下不同功率密度的900MHz射频电磁波照射下单个活态人红细胞膜弯曲弹性模量(Kc)和剪切弹性模量(μc)。结果150mW/m2和310mW/m2的900MHz射频电磁波在35℃、37℃和40℃照射30min前后,红细胞的Kc和μc都没有显著变化(P>0.05)。10000mW/m2和50000mW/m2的900MHz射频电磁波照射30min后,红细胞的Kc和μc都显著升高(P<0.05),并且在35℃和40℃时升高的幅度大于37℃时升高的幅度。结论环境温度变化和一定功率密度的射频电磁波照射对红细胞膜力学特性的影响具有相互协同增强作用。Objective To study the synergetic effects of 900 MHz radio-frequency electromagnetic wave (RF-EMW) and environmental temperature on membrane mechanical properties of single living intact human red blood cell (RBC). Methods The membrane bending elastic modulus (Kc) and shear elastic modulus (μc) of single living intact RBC, which were exposed to 900 MHz RF-EMW at different power densities at 35, 37 or 40 ℃, were observed and measured by multi-dimensional micro-imaging technique and micro dynamic imaging analysis technique. Results There were no significant differences of Kc or μc of RBC membrane before and after 150 mW/m2 and 310 mW/m2 RF-EMW exposure for 30 minutes at 3 temporature conditions respectively (P>0.05). Both Kc and μc were increased significantly after 10 000 mW/m2 and 50 000 mW/m2 RF-EMW exposure for 30 minutes at 3 temperature conditions respectively (P<0.05). The rates of increase (Kc or μc ) at 35 ℃ and 40 ℃ were greater than those at 37 ℃. Conclusion There are synergetic effects of environmental temperature and 900 MHz RF-EMW with some power densities on membrane mechanical properties of single living intact human RBC.

关 键 词：射频电磁波 温度 红细胞膜 力学性质 弹性模量 

分 类 号：R135.99[医药卫生—劳动卫生]