糖预处理治疗减轻术后胰岛素抵抗的价值  

Value of preoperative carbohydrate loading and new preoperative fasting protocol on reducing insulin resistance in patients following abdominal surgery.

作　　者：朱岭[1] 彭开勤[1] 张应天[1] 全卓勇[1] 龚少敏[1] 许涛[1] 

机构地区：[1]武汉市第六医院普外科,430015

出　　处：《中国实用外科杂志》2005年第6期359-361,共3页Chinese Journal of Practical Surgery

摘　　要：目的观察腹部外科手术病例进行术前糖预处理及应用新的禁食方案等治疗方法对减轻术后胰岛素抵抗的价值。方法对2003年3月至2004年12月采用Quicki法测定191例腹部手术后病人胰岛素敏感性,前瞻性对比术前进行糖预处理及应用新的禁食方案病例组(88例)与对照组(103例)在术后胰岛素抵抗方面的差异,以t检验比较两组间差异的显著性。结果治疗组术后胰岛素抵抗程度及持续时间均明显低于对照组(P<0.05)。结论腹部手术后早期胰岛素抵抗是机体应激反应的表现,手术后长时间胰岛素抵抗不利于术后恢复。术前糖预处理治疗可有效降低围手术期胰岛素抵抗程度,缩短胰岛素抵抗时间,有助于病人早期康复。Objective To evaluate the value of reducing insulin resistance by preoperative carbohydrate loading and new preoperative fasting protocol in patients following abdominal surgery.Methods The insulin sensitivity of 191 patients following abdominal operation was detected by Quicki method.The insulin sensitivity in the group treated by preoperative carbohydrate loading and new preoperative fasting protocol (88 cases) was compared with that in the control group (103 cases).The difference of postoperative insulin sensitivity was analyzed by t test.Results The therapy group showed lower degree and shorter duration of insulin resistance (P<0.05).Conclusion Postoperative insulin resistance is the result of surgical stress.Long-term insulin resistance following operation has an adverse effect on recovery.Preoperative carbohydrate loading and new preoperative fasting protocol can reduce the degree and course of insulin resistance,so the rehabilitation can be facilitated.

关 键 词：腹部手术 胰岛素抵抗 腹部外科 糖预处理 外科手术 

分 类 号：R656[医药卫生—外科学]