改良三甲散对血管性痴呆病患者智能状态的调节作用  

Modified Sanjiasan Decoction in Regulating Intelligence State of Patients with Vascular Dementia

作　　者：刘涛[1] 王灿晖[1] 杨进[1] 吴瑞枝[2] 邵风扬[3] 姚文龙[4] 夏晨[4] 

机构地区：[1]南京中医药大学,南京210029 [2]南京脑科医院 [3]江苏省连云港市中医院 [4]江苏省中医院

出　　处：《中国中西医结合杂志》2005年第6期492-495,共4页Chinese Journal of Integrated Traditional and Western Medicine

基　　金：江苏省中医药局项目(No.H-020)

摘　　要：目的研究改良三甲散对血管性痴呆病(VD)的治疗作用。方法治疗组37例,改良三甲散煎服,每天1剂;对照组31例,脑复康每次0.8g,每天3次口服;疗程3个月。观察指标为长谷川痴呆量表(HDS)、简易智力状态检查表(MMSE)及MMSE分项记分,智商、记忆商。结果改良三甲散能提高患者HDS、MMSE测试总成绩和MMSE单项计分成绩(P<0.05或P<0.01),改善患者的痴呆状态(P<0.05),提高患者的智商(P<0.05)和记忆商(P<0.01)。结论改良三甲散具有一定的益智、抗痴呆作用。ObjectiveTo investigate the therapeutic effects of modified Sanjiasan decoction (MSD) on vascular dementia (VD). MethodsThirty-seven patients in the treated group were given MSD, one dosage each day, and 31 patients in the control group were administered orally Naofukang 0.8 g three times a day. The treatment course for both groups was three months. The indices as Hasegawa dementia scale (HDS), mini mental state examination (MMSE) and its subentries, intelligence quotient (IQ) and memory quotient (MQ) were examined. ResultsMSD could improve the scores of HDS, MMSE and its subentries (P<0.05 or P<0.01), ameliorate dementia state and enhance IQ (P<0.05) and MQ (P<0.01) in patients with VD. ConclusionMSD has a certain effect on intelligence benefiting and dementia antagonizing.

关 键 词：改良三甲散 痴呆病 血管性 患者 调节作用 智能状态 长谷川痴呆量表 MMSE 抗痴呆作用 治疗作用 观察指标 智力状态 0.05 痴呆状态 记忆商 治疗组 对照组 脑复康 检查表 HDS 智商 成绩 

分 类 号：R277.7[医药卫生—中医学]