运动心脏重塑过程中的机械-生化偶联机制  

Mechanism of Mechanical Stretch-Biochemistry in the Restructure of Exercise-Induced Cardiomyocyte Hypertrophy

作　　者：王丽君[1] 徐岩[1] 李国岩[1] 毕永锋[1] 

机构地区：[1]山东烟台师范学院体育系,山东烟台264025

出　　处：《广州体育学院学报》2004年第4期34-36,共3页Journal of Guangzhou Sport University

摘　　要：离体实验证明 ,心肌在不受神经体液因子的作用下 ,仅受牵张刺激也能导致心肌肥大反应。运动时心室舒张末期容积增加类似离体的牵张刺激 ,提示运动心脏重塑过程中 ,可能也存在某种机械 -生化偶联机制在心肌蛋白质合成中发挥作用。Experiment in vitro demonstrates mechanical stretch can induce cardiomyocyte hypertrophy without receiving nervous hormonal regulation.The increase of ventricle dimension in exercise resembles mechanical strech in vitro. Mechanism of mechanical stretch-biochemistry maybe play an important role in the restructure of exercise-induced cardiomvocyte hyqertrophy.

关 键 词：运动心脏 机械-生化偶联 心肌肥大 

分 类 号：G804.7[文化科学—运动人体科学]