正常人和结石病人尿中不同分子量的分离物对草酸钙晶体的影响  

The effects of urinary macromolecule in calcium stone formers and normal controls for the growth and agglomeration of calcium ox-alate monohydrate(com)crytals.

作　　者：辛殿旗[1] 冯陶[1] 窦长琪[1] 沈绍基[1] 

机构地区：[1]北京医科大学泌尿外科研究所

出　　处：《中华实验外科杂志》1994年第6期343-344,共2页Chinese Journal of Experimental Surgery

基　　金：课题国家自然基金

摘　　要：尿中不同分子量的大分子分离物，由于分子量、化学结构、化学性质的不同，对尿石形成的作用也不相同。而分子量相同的大分子分离物，正常人和病人也有明显的差异。作者认为这种差异是结石形成的一个重要因素，也是我们进一步探讨尿石症发病机理的一个新突破口。Urinary macromolecules include variedinhibitors and promoters of urinary stone,which can change the kinetic process of crystalnucleation, growth and agglomeration due todifferent molecular weights structures andconditions of actions thus resulting in inhibit-ing or promoting the formation of urinary stone.This paper determines by the particle size distribution measuring technique,the effect of macromolecules with different molecular weight in the urine of normal controls andstone formers on formation of COM,with an attempt to find out the qualitative and quanti-tative difference urinary macromolecules be-tween normal controls and stone formers andtheir functions in the stone formation.

关 键 词：含钙尿石 尿结石 大分子分离物 晶体 抑制指数 

分 类 号：R691.402[医药卫生—泌尿科学]