猪苓多糖联合乙肝疫苗治疗慢性乙型肝炎对血清HBV标志的影响  

THE EFFECT OF ZHULING DUOTANG AND HEPATITIS B VACCINE ON SERUM HBV MARKERS IN PATIENTSWITH CHRONIC HEPATITS B

作　　者：郑邦德[1] 刘逢举[1] 肖萍[1] 谢晨[1] 杨彦林[1] 郭振华[1] 

机构地区：[1]兰州医学院传染病研究室

出　　处：《中华消化杂志》1994年第1期8-9,共2页Chinese Journal of Digestion

摘　　要：观察了猪苓多糖联合乙肝疫苗治疗慢性乙型肝炎对患者血清ＨＢＶ标志的影响。治疗结束后半年，治疗组ＨＢｓＡｇ、抗－ＨＢｃ，ＨＢｅＡｇ和ＰＨＳＡ－Ｒ的阴转率分别为６０％，０，２３．１％和１８．８％。抗－ＨＢｓ无１例阳转，无１例ＨＢＶ标志全部阴转者。对照组分别为３．９％，０，１９．３％和１６．３。亦无１例产生抗－ＨＢｓ。两组ＨＢＶ标志的转换率差异无显著性（Ｐ＞０．０５）。结果表明：猪苓多糖联合乙肝疫苗对清除和抑制ＨＢＶ无明显效果。his article observes the effect of combined use of ZHULING DUOTANG and hepatitis Bvaccine on serum HBV markers.Half year after discontinuation of the therapy,the clearance rateof HBsAg,HBcAb,HbeAg and PHSA-R is 6.0%,0,23.1%and l8.8% respectively. The clearancerate of control group is 3.9%,0,19.3%and l.3% rspectively. No positive HBsAb is observed.Thereis no significant difference in seroconversion rate of HBV markers between both groups(P>0.05).The results showed that the combined use of ZHULING DUOTANG and hepatitis B vaccinehave not definite effect on the removing and inhibiting of HBV.

关 键 词：猪苓多糖 乙型肝炎 疫苗 病毒 

分 类 号：R512.62[医药卫生—内科学]