韶关市健康人群百日咳、白喉和破伤风抗体水平监测  

Monitoring on antibody levels of pertussis, diphtheria and tetanus in healthy population of Shaoguan

作　　者：黄辉[1] 胡国超[1] 邓俊兴 

机构地区：[1]广东省韶关市疾病预防控制中心,广东韶关512026

出　　处：《疾病监测》2005年第3期128-129,共2页Disease Surveillance

摘　　要：目的　了解韶关市健康人群百日咳、白喉和破伤风免疫状况,及时为免疫策略提供科学依据。方法　随机抽查部分0～4 0岁健康人群进行了百日咳、白喉和破伤风抗体水平监测。结果　百日咳抗体几何平均滴度GeimetricMeanTiter(GMT)和抗体保护率分别为1∶374 2、6 7 74 % ;白喉、破伤风抗毒素GMT分别为0 16 99IU/ml、0 180 4IU/ml,阳性率分别为88 94 %、91 83%。结论　对百日咳、白喉和破伤风已经形成了较好的免疫屏障,但人群百日咳抗体水平偏低,应大力推广应用吸附无细胞百日咳、白喉。Objective This study was intended to understand the status of immunization against pertussis, diphtheria and tetanus in healthy population and provide a timely scientific basis for immunization strategy.Methods A number of healthy people aged between 0-40 were randomly selected to undergo monitoring antibody levels of pertussis, diphtheria and tetanus.Results The geometric mean titer (GMT) and rate of protection for pertussis antibody were 1:374.2 and 67.74%, respectively; GMT of diphtheria and tetanus antitoxin was 0.1699IU/ml and 0.1804IU/ml, with a positive rate of 88.94% and 91.83%, respectively.Conclusion A good immunological barrier against pertussis, diphtheria and tetanus has formed, but the antibody level of pertussis among people is a little lower, therefore we should strongly extend the use of Adsorbed Diphtheria,Tetanus and Acellular Pertussis Combined Vaccine.

关 键 词：百日咳 白喉 破伤风 抗体水平 韶关市 监测 

分 类 号：R181.8[医药卫生—流行病学]