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作 者:刘锦纷[1] 丁文祥[1] 苏肇伉[1] 张海波[1]
出 处:《中华胸心血管外科杂志》1994年第3期193-195,共3页Chinese Journal of Thoracic and Cardiovascular Surgery
摘 要:1989年11月至1992年7月期间,应用低温保存同种带瓣大动脉纠治儿童复杂性先心病12例。病人年龄2~16岁(7.2±3.7岁),体重8~31.5kg(18.9±6.6kg)。诊断为法乐氏四联症(TOF)8例,其中伴肺动脉瓣闭锁3例;冠状动脉畸形1例;严重肺动脉发育不良2例;左肺动脉缺如2例。大动脉错位伴室间隔缺损和肺动脉狭窄2例;永存动脉干畸形(Ⅱ型)2例。8例应用同种带瓣管道作右室流出道与肺动脉连接,4例应用同种带瓣肺动脉片作跨瓣环右室流出道扩大术。本组死亡1例,最长随访时间3年。文中对同种带瓣管道的取材方法,保存技术及应用方法作了讨论。Cryopreserved conduit valved homograft was used in 12 patients between November 1989 and July 1992. Ages ranged from 2 to 16 years (mean 7.2± 3.7 years) and weight varied from 8.0 to 31.5kg (mean 18.9±6.6kg) at the time of operation.The diagnosis included: 8 cases of tetralogy of Fallot (TOF) (3 cases of TOF with pulmonary atresia, 1 case of TOF with anomaly of coronary artery, 2 cases of TOF with left pulmonary atresia, 2 cases of TOF with severe pulmonary hypoplasia);2 cases of transposition of great arteries with ventricular septal. defect and pulmonary stenosis; 2 cases of truncus arteriosus (type Ⅱ). In 8 patients the right ventricular outflow tract was connected to the pulmonary artery with a valved homograft conduit. In the other 4 patients transannular patch repair with a single valved pulmonary homo graft was performed. There was one operative death. The longest follow-up study on 1 patient 3 ycars after operation showed encouraging results.Method of collection and cryopreservation techniques of VHC and the opertative procedures were discussed.
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