房间隔缺损修补术前后肺功能改变及其意义  

Changes of Preoperative and Postoperative Pulmonary Functions and Their Significance in Patients with Atrial Septal Defect

作　　者：王宁夫[1] 陈长熙[1] 于润江[1] 杨耀晨 

机构地区：[1]沈阳中国医科大学第一附属医院心脏科,沈阳中国医科大学第一附属医院呼吸疾病研究所

出　　处：《中华胸心血管外科杂志》1994年第3期199-201,共3页Chinese Journal of Thoracic and Cardiovascular Surgery

摘　　要：研究３０例房间隔缺损病人心肺血流动力学改变和外科修补术对肺功能的影响。肺动脉压正常和轻度升高者，术前弥散功能异常增高，术后降至正常。肺动脉压严重增高者虽有肺血增多，但未见弥散功能异常增高者，术后亦无明显变化。术前随着肺动脉压升高，用力呼气１秒量和肺活量逐渐降低，术后未见好转，但术后肺容量明显改善。Influence of cardiopulmonary hemodynamics and surgical closure of the atrial septal defect on pulmonary ventilation, volume changes and diffusion function were studied in 30paticnts with atrial septal defect. In Group A, patients with mean pulmonary arterial pressure (MPAP)<2.5kPa (20mmHg), and in Group B, with MPAP 2. 7～3.9kPa (20～29mmHg). All of the patients in these two groups had high diffusion function which became normal after surgical correction. In Group C, the patients with MPAP>4.0 kPa (30 mmHg) showed normal diffusion function both preoperatively and postoperatively. In Group A, patients with normal MPAP, the pulmonary ventilation function was normal. In Group B, the postopreative FEV1.0 was markedly increased. In Group C, as pulmonary artery pressure increased before operation there was a progressive reduction in the first second forced expiratory volume (FEV1.0) and vital capacity. These abnormalities were not corrected after operation, but there was an improvement in pulmonary volume.

关 键 词：房间隔缺损 肺动脉高压 肺功能 

分 类 号：R654.2[医药卫生—外科学]