鸡实验性急性有机磷中毒血清酶活性变化分析  

The Analysis of Serum Enzyme Activity Change in Chicken Acute Organic Toxicosis Test

作　　者：刘艳卉[1] 杨君宁[2] 傅童生[1] 

机构地区：[1]湖南农业大学动物科技学院,湖南长沙410128 [2]广东省农业科学院兽医研究所

出　　处：《畜牧兽医杂志》2005年第4期1-2,共2页Journal of Animal Science and Veterinary Medicine

摘　　要：选取临床健康体质量为0.8±0.07kg的三黄肉鸡24只,随机分成3个试验组和1个对照组,每组6只,其中试验、和组分别皮下一次注射氧乐果攻毒,剂量分别为35mg/kg体质量、70mg/kg体质量和140mg/kg体质量;对照组注射生理盐水。攻毒后系统观察动物急性有机磷中毒症状,采血测定体内胆碱酯酶(CHE)、碱性磷酸酶(ALP)、乳酸脱氢酶(LDH)、谷丙转氨酶(ALT)以及谷草转氨酶(AST)的活力。试验结果表明:鸡急性有机磷中毒主要表现为精神沉郁,共济失调,口角大量流涎,呼吸困难,严重腹泻和粪便带血等临床症状。攻毒组CHE3活性显著低于对照组,ALP的活性也有所降低,LDH活性升高,但ALT和AST的活性无显著变化。24 chicken in good condition were randomly divided into one control group and three toxic groups,and pergroup6,their average weight is 0.8±0.05kg,toxic group ⅠⅡⅢ are given Omethoate 3570140mg/kg with hypodermic injection respectively.Control group was injected with physiological saline.After toxin given,Observe the clinical signs and symptoms,blood samples were collected for CHEALPLDHALT and AST.The clinical symptoms are hyponoin,ataxia, salivate,decompensation,severe diarrhea and with blood in the dejecta.Serum CHE activity of toxic groups are significantly lower than control group and ALP activity is also lower,But LDH activity is a litte higher,there were not significant alteration in serum ALT and AST among all groups.

关 键 词：有机磷中毒 血清酶活性 变化分析 急性 实验性 碱性磷酸酶 乳酸脱氢酶 谷草转氨酶 谷丙转氨酶 体质量 三黄肉鸡 生理盐水 中毒症状 系统观察 胆碱酯酶 试验结果 呼吸困难 临床症状 对照 试验组 攻毒 氧乐果 ALP LDH AST 

分 类 号：S858.23[农业科学—临床兽医学] X550.322.5[农业科学—兽医学]