70例沙雷菌感染鉴定及药敏分析  

Bacteria identiflcation and antibiotic susceptability anal ysis of 70patients infected with serratia

作　　者：张正[1] 赵素蕊[1] 王贺[1] 闫薇 刘文芸 王丽云 

机构地区：[1]北京医科大学人民医院检验科

出　　处：《中华医学检验杂志》1994年第6期359-361,共3页

摘　　要：自１９９０年以来，从临床标本中分离到７０株沙雷菌，分别为粘质沙雷菌、居泉沙雷菌、液化沙雷菌及红色沙雷菌。经对主要生化反应的百分率进行分析，并对２０种抗生素药敏检测结果表明，敏感抗生素有泰宁、环丙氟哌酸、头孢三嗪、丁胺卡那霉素、硫苯咪唑青霉素及氧哌嗪青霉素等；一代头孢菌素及氨苄青霉素耐药；庆大霉素、妥布霉素等几种抗生素的耐药性有增强趋势。通过对中敏药物加大剂量仍有较好疗效。并通过药敏检测对部分院内感染的同源性进行了探讨。Since 1990,we have isolated from clinical specirneris,70 strains of serratia,which,with the inci-dence of descending frequency were S.fonticola,S,lique faciens,S. rubldeae 42.86%of the patients were immunocompromised.Positivities of various biochemical reactions have been analvzed in the auto-mated bacteria identification system.We have also tested the sensitivities to 20 antibiotics,in which the most sensitive ones were imipenem,ciprofloxacin, ceftriaxone,amikacin,mezlacillin and piperacillin.Those resisted mostly were cefamadole,cephalothin and ampicillin. The resistance to gentamicin,to-bramycin,ticarcillin and cdftazidine increased year by year。70%antibiotic administrations were re-ferred to antibiotic susceptability test.Intermediately sensitive antibiotics had relatively good treatment results as the doses increased.The control of serratia infection was generally not difficult and only a few cases might become persistent bacterium-carriers.

关 键 词：沙雷菌属 鉴定 药敏试验 

分 类 号：R927.1[医药卫生—药学] R378.2