献血者三种病毒感染血液学筛查分析  

Analysis of virial infection rates among blood donors

作　　者：王吉勇[1] 赵秀华[1] 李克成[1] 

机构地区：[1]荣成市人民医院,山东荣成264300

出　　处：《中国实验诊断学》2005年第3期345-346,共2页Chinese Journal of Laboratory Diagnosis

摘　　要：目的探讨献血者单纯疱疹病毒(HSV)、巨细胞病毒(CMV)、风疹病毒(RV)感染状况及其血液学筛查的意义,进一步提高所供血液的质量。方法采用荧光定量聚合酶链反应技术,检测献血者血液中三种病毒的特异核酸载量。其中有偿献血者140例,(男、女各70例);无偿献血者140例(男、女各70例)。结果有偿献血者HSV感染男、女阳性率分别为1·4%,2·8%;CMV感染男、女阳性率分别为2·8%,5·7%;RV感染男、女阳性率分别为0·0%,1·4%。无偿献血者HSV感染男、女阳性率分别为0·0%,1·4%;CMV感染男、女阳性率分别为0·0%,2·8%;RV感染男、女阳性率均为0·0%。结论有偿献血者三种病毒感染阳性率高于无偿献血者。Objective To explore the virial infections of herpes simpiex virus(HSV), rubella virus(RV) and cytomegals virus among blood donors(paid doners, voluntary non-remunerated donors) so as to increase the safety of the blood supply. Methods The virial load of HSV, RV and CMV in total 280 blood donors, including 140 paid donors(70 males, 70 females) and 140 voluntary nonremunerated donors, were detected by fluorescence quantitive polymerase chain reaction(FQ-PCR). Results The positive rates of HSV, RV and CMV infections among paid doners were 4.2%(1.4% in males, 2.8% in females), 1.4%(zero in males, 1.4% in females) and 8.5%(2.8% in males, 5.7% in females), respectively. And the positive rates of HSV and CMV infections in female voluntary nonrenumerated donors were 1.4%, 2.8% respectively. But there were no infections for RV in both non-remunerated doners and female ones, and for HSV and CMV in male voluntary non-remunerated donors. Conclusion This stydy shows that the positive rates of HSV, RV and CMV infections in paid donors are higher than in voluntary non-remunerated donors and that there are a need on paying attention to donor recruitment and selection strategies for the sarety of blood supply.

关 键 词：病毒 感染 献血者 荧光定量聚合酶链反应(FQ-PCR) 

分 类 号：R446.5[医药卫生—诊断学]