心脏病患者血清七种元素含量与血压及生化指标的关系  

Seven elements in patients with heart diseases andtheir relationship with blood pressure and biochemicaltarget

作　　者：何邦平[1] 赵德山[1] 赵霖[1] 王颖[1] 王桂清[1] 鲍善芬[1] 李东方[1] 邓欣新 邓京丰 王敏[1] 蒋珠富[1] 李闻捷[1] 

机构地区：[1]上海第二军医大学化学教研室,上海第二军医大学长海医院,中国人民解放军总医院

出　　处：《中华医学杂志》1994年第8期492-494,共3页National Medical Journal of China

基　　金：国家自然科学基金

摘　　要：我们检测了心脏病患者血清微量元素Ｚｎ、Ｃｕ、Ｆｅ和常量元素Ｋ、Ｎａ、Ｃａ、Ｍｇ的含量，并与血压及生化指标作相关分析。结果发现心脏病患者Ｋ和Ｃａ／Ｍｇ显著低于对照组，而Ｎａ、Ｍｇ、Ｚｎ、Ｆｅ和Ｎａ／Ｋ、Ｚｎ／Ｃｕ则显著高于对照组。Ｋ、Ｃａ／Ｍｇ与血压呈负相关，而Ｎａ、Ｚｎ、Ｆｅ、Ｚｎ／Ｃｕ和Ｎａ／Ｋ与血压呈正相关；Ｆｅ与红细胞压积（Ｈｃｔ）呈正相关；Ｚｎ／Ｃｕ与Ｈｃｔ、甘油三酯、极低密度脂蛋白均呈正相关，而与高密度脂蛋白呈负相关。The trace elements Zn, Cu, Fe, and ordinary ele-ments K, Na, Ca, Mg in serum of 711 patients withheart disease (HD) were detennined with GGX-II atomic absortption spectrophotometer and flame pho-tometer. It was found that the contents of K,Ca/ Mg in HD were significantly lower than thosein the control, while the content of Na, Mg, Zn, Fe,and Zn / Cu, Na / K were significantly higher thanthose in the control. There was a significantly nega-tive correlation between K, Ca / Mg and blood pres-sure (BP), between Zn/Cu and HDL-ch, and asignificantly positive correlation between Na, Zn, Fe,Zn / Cu, Na / K and BP, between Fe and Hct, be-tween Zn / Cu and Hct, TG, VLDL-ch.

关 键 词：心脏病 微量元素 血压 

分 类 号：R541[医药卫生—心血管疾病]