N市饮用水中非挥发性有机物致突变性研究  

Study on Mutagenicity of Nonvolatile Organic Compounds of Drinking Water in N City

作　　者：闫鹏[1] 于梅[1] 郑剑[1] 徐景野[1] 

机构地区：[1]宁波市疾病预防控制中心,浙江315010

出　　处：《中国预防医学杂志》2005年第3期196-198,共3页Chinese Preventive Medicine

基　　金：宁波市科委资助项目(2003060)

摘　　要：目的探讨N市饮用水中非挥发性有机物的致突变性。方法应用XAD-2大孔树脂吸附浓集水中有机物的技术,结合Ames试验、微核实验、小鼠精子畸形实验,研究了N市主要水厂水源水、滤池出水、氯化消毒自来水中非挥发性有机物(NOCs)的致突变性。结果氯化消毒自来水50L/ml剂量组微核率和精子畸形率显著高于阴性对照组(P<0·05),氯化消毒自来水5L/皿剂量下,TA98-S9MR=4·92,TA98+S9MR=2·69。结论氯化消毒自来水有一定程度致突变性,水源水、滤池出水未检出致突变性,氯化消毒使水质的诱变性增高。Objective To study the mutagenicity of the nonvolatile organic compounds(NOCs)in drinking water in N city. Methods XAD-2 resin were used to extract the organic matters in water.The Ames test,the micronucleus assay and the sperm morphologic test were used to analyze the mutagenicity of the nonvolatile organic compounds(NOCs)in water,for the main waterworks' source water,the clarified filtration water and the chlorinated tap water in N city. Results When the chlouinated tap water dosage was 50L/ml,micronucleus rate and seed deformity rate were significantly higher than that in normal group(P<0.05).When the chlorinated tap water dosage were 5L/plate,TA 98-S9 MR=4.92,TA 98+S 9 MR=2.69. Conclusions The chlorinated tap water were showed Mutagenicity in some degree,but there were not mutagenicity found in the source water and the clarifying fillration water.Chlorination can enhance mutagenicity of tap water.

关 键 词：N市 饮用水 非挥发性有机物 致突变性 消毒 诱变力试验 

分 类 号：R123.1[医药卫生—环境卫生学]