血清抗结核抗体筛检消化疾病患者结核杆菌感染的临床意义  

Screening Tubercle Bacillus Infection in Patients with Various Digestive Diseases by TBAb Test in Serum:Clinical Significance

作　　者：王志红[1] 李虹义[1] 韩英[1] 纪欣[1] 武子涛[1] 

机构地区：[1]北京军区总医院消化内科,北京100700

出　　处：《华北国防医药》2005年第3期164-166,共3页Medical Journal of Beijing Military Region

摘　　要：目的:研究不同结核杆菌抗原在消化疾病患者中的感染状况及检测抗结核抗体的临床意义。方法:检测23例结核病和425例消化疾病患者血清中3种抗结核抗体阳性率,并与结核菌素试验和红细胞沉降率(ESR)检查结果进行比较。结果:结核病和消化疾病3种抗结核抗体联合检测阳性率分别是60.9%和21.6%,二者差异显著(P<0.01),消化疾病与结核病比较,除息肉无显著差异(P>0.05)外,其余各病均差异显著(P<0.01)。在抗结核抗体阳性者中,38例结核菌素试验者22例阳性,与抗结核抗体阳性一致率为57.9%;94例ESR检查者37例增快,与抗结核抗体一致率为39.4%。结论:联合检测多种血清抗结核抗体是筛检消化疾病患者结核抗原感染的辅助诊断手段。Objective:To investigate the state of infection with different tubercle bacillus antibodies (TBAb) in patients with various digestive diseases and to evaluate the clinical significance of TBAb test.Methods:Three TB antibodies (TBAb) in serum of 23 patients with tuberculosis and 425 cases with different digestive disease were determined jointly.The consistence between the positive reaction to TBAb,and the findings of PPD test and ESR results was analyzed.Results:There was significant difference in the positive reaction of these TBAb between the group with tuberculosis (60.9 %) and the group with different digestive ailments (21.6 %)(P<0.01).In positive rate of TBAb test,the subgroups of these digestive ailments had significant differences compared with the group with tuberculosis (P<0.01) except for the subgroup with gastrointestinal polyps (P>0.05).In the patients with positive TBAb test,the PPD test was positive in 22 patients out of 38 cases,and the consistence was 57.9%;ESR in 35 patients became faster out of 94 cases,and the consistence is 37.2 %.Conclusions:The joint determination of various TBAb in serum was a supplementary diagnostic method to screen those infected with tubercle bacillus in patients with various digestive diseases.

关 键 词：消化系统疾病 结核 抗结核抗体 抗原 

分 类 号：R446.62[医药卫生—诊断学] R57[医药卫生—临床医学]