不同来源膳食纤维、钙与结直肠癌关系的研究  

A Case-control Study on Colorectal Cancer and Dietary Fiber and Calcium of Various Sources

作　　者：杨工[1] 高玉堂[1] 季步天[1] 金凡[1] 项永兵[1] 郑树[1] 

机构地区：[1]浙江医科大学肿瘤研究所,上海市肿瘤研究所

出　　处：《中华预防医学杂志》1994年第4期195-198,共4页Chinese Journal of Preventive Medicine

基　　金：上海市科学技术发展基金;部分由国家"八五"科技攻关项目

摘　　要：以一项基于全人群的营养流行病学病例对照研究数据，探讨不同食物来源的膳食纤维和钙与结、直肠癌联系性的可能差异。结果表明，蔬菜类膳食纤维与左、在半结肠癌和直肠癌，水果类膳食纤维与右半结肠癌均呈显著负相关；动物性膳食钙则具有降低左、右半结肠癌及直肠癌发病相对危险度的趋势。并经非条件Ｌｏｇｉｓｔｉｃ回归模型调整年龄、性别、总能量、维生索Ｃ、饱和脂肪酸等因素后上述联系仍然存在，提示为一类独立性变量。而谷类膳食纤维和植物性膳食钙的抗结直肠癌的保护性作用不显著。研究表明膳食纤维和钙对结直肠癌的保护性作用，不但与摄入量还与种类和来源密切相关。．．population-based case-control study was conducted in 726 incident cases with colorectal cancer and 1400 controls matched on age and sex in Shanghaj, to explore the possible difference in associations between colorectal cancer and dietary fiber and calcium of various sourees.The results showed reverse correlation between intake of vegetable fiber and ascending and descending colon cancer and rectal can-cer, and between intake of fruit fiber and ascending colon cancer only.Dietary intake of calcium from animal sources could reduce the relative risk of ascending and descending colon caneer.These associa-tions still existed after adjustment of the effects of the factors such as age,sex,intakes of total calorie,vitamin C, saturated fatty acid, etc. with logistic regression model, which indicated all of those variables were independent of other ones.Intake of dietary fiber from grains and calcium from plant sources had no significant protection from colorectal cancer.This study also showed the protective effects of dietary fiber and calcium on colorectal caneer not onlv correlated to their intake, but also closely to their sorts and sources.

关 键 词：结肠肿瘤 直肠肿瘤 饮食纤维钙 

分 类 号：R735.3[医药卫生—肿瘤]