脂肪小珠皮下注射的实验研究和临床应用  

Subcutaneous injection of fatty tissue pearls——experimental study and clinical applications

作　　者：鲍卫汉[1] 张宗学[1] 孙晓光[2] 赵惠勇[1] 朱洪荫[1] 

机构地区：[1]北京医科大学第三医院成形外科研究中心,100083 [2]航空航天部三院731医院整形外科

出　　处：《中华整形烧伤外科杂志》1994年第5期364-367,共4页

摘　　要：雌性大鼠20只,自每只盆腔二侧分别取出脂肪0.6 g 或1.2 g 一块,一块剪成2 mm 大小后注入左背皮下,另一块整块植入右背部皮下。随机分4组,分别观察3、6、12、24周。24周时,左侧为原重的21.1％,右侧为6.9％,左侧优于右侧(P<0.05)。镜下显示随时间延长,脂肪组织坏死灶逐渐扩大,并形成较大囊肿,新鲜囊肿边缘为残存的脂肪细胞,陈旧者被纤维细胞包围,囊内空虚,纤维间隔和包膜随时间延长而增厚。临床应用取自下颌和腹部等部位的皮下脂肪,剪成2～3 mm 后注入眉间、鼻唇沟等凹陷处,共15例27个部位。随访6个月,51.9％较满意,18.5％尚可,29.6％无效同注射前。In 20 female adult rats,fatty tissue of 0.6 or 1.2g was taken from each side of the pelvis.One fatty block,after being cut into pearls of about 2mm in diameter, was injected subcutaneously to the left side of the back while another was transplanted en bloc in the right side.The rats were randomized into four groups and samples of fat were taken at 3,6,12 and 24 weeks.After 24 weeks,the sample from left side was found to be 21.1% of its original weight while the right side was only 6.9%(P<0.05).In clinical practice,subcutaneous fat was sucked out from submandibular or abdominal re gions,cut into pearls of 2～3mm in diameter and injected to depressed area,such as glabella or naso-labial grooves.The procedure was applied to 27 sites of 15 cases.Fol- low-up of 6 months showed satisfactory results in 51.9%,acceptable in 18.5% and no effect in 29.6%.

关 键 词：脂肪 皮下注射 实验 临床应用 

分 类 号：R622[医药卫生—整形外科]