杏丁注射液对突发性耳聋病人血液流变学和血清SOD LPO的影响  

THE EFFECTS OF XIN-DING INJECTION TO HEMORHEOLOGY AND SERUM SOD LPO OF PATIENT WITH SUDDEN DEAFNESS

作　　者：张向阳[1] 钱欣梅[1] 季念英[1] 

机构地区：[1]济宁医学院生物化学教研室

出　　处：《济宁医学院学报》2005年第2期23-25,共3页Journal of Jining Medical University

摘　　要：目的观察杏丁注射液对突发性耳聋病人血液流变学和血清SOD活性、LPO含量的影响。方法将152例突发性耳聋患者随机分为两组,杏丁注射液治疗组86例,对照组66例,检测各组治疗前后血液流变学、血清SOD活性和LPO含量。结果突发性耳聋病人杏丁注射液治疗组有效率为89.53%,对照组74.24%(P<0.01),经杏丁注射液治疗后血液粘度下降、血清SOD活力提高、LPO含量下降,均优于对照组(P<0.05;P<0.01)。结论杏丁注射液是治疗突发性耳聋的有效药物,能改善突发性耳聋病人的血液流变学,并具有清除自由基提高SOD活力的作用。Objective To observe the effect of xin-ding Injection to hemorheology and serum SOD,LPO of patients with sudden deafness.Methods One hundred and fivty-two patients suffering from sudden deafness were random divided into two groups, 86 case were injected xin-ding Injection( treated groups) and other 66 case used western medicine alone(control/groups),Same time, blood hemorheology and serum SOD?LPO were measured in all patients.Results The total effective rate of the treated group was 89.53%, that of the control group was 74.24%(P<0.01),After xin-ding Injection treatment, decrease the blood viscosity and serum LPO , increase the activity of SOD . There was a statistical significance compared with that of control group (P<0.05,0.01).Conclusion Xin-ding Injection was very effective in treating sudden deafness, It could improve hemorheology and keep the blood supply for inner ear and clear away the free radicals so as to reduce the damage of inner ear.

关 键 词：杏丁注射液 突发性耳聋 血液流变学 LPO 血清SOD 病人 SOD活性 SOD活力 清除自由基 对照组 耳聋患者 治疗前后 血液粘度 0.05 有效药物 治疗组 含量 有效率 治疗后 下降 

分 类 号：R259.414[医药卫生—中西医结合] R764.437[医药卫生—中医内科学]