异丙酚-氯胺酮复合静脉麻醉在小儿中小手术中的应用  

Application of propofol-ketamine combined intravenous anesthesia in children's mini-middle-operations

作　　者：廖永强[1] 张曙[1] 石海燕[1] 谢淑芬[1] 

机构地区：[1]广东省东莞市人民医院麻醉科,广东东莞523018

出　　处：《实用医院临床杂志》2005年第3期38-39,共2页Practical Journal of Clinical Medicine

摘　　要：目的观察异丙酚-氯胺酮复合静脉麻醉与单纯氯胺酮麻醉在小儿中小手术中对呼吸循环功能及术后恢复情况的影响.方法30例中小手术患儿分成两组:异丙酚-氯胺酮(PK)组15例,术中异丙酚4～6 mg/(kg·h)与氯胺酮2～3 mg/(kg·h)混合液持续静脉泵入;氯胺酮(K)组15例,术中氯胺酮1～2mg/(kg·h)间断静脉注射.结果术中PK组循环功能较K组稳定,术中发生肢体不自主运动及眼球震颤较K组少;PK组术中氯胺酮用量、术后恢复时间与K组比较,差异有显著性意义(P＜0.05).结论异丙酚-氯胺酮复合静脉麻醉能使小儿中小手术麻醉更平稳、术后苏醒更快,更适合于小儿中小手术的麻醉.Objective To observe the influence of propofol-ketamine combined intravenous anesthesia and ketamine intravenous anesthesia on breath and circulation functions and the postoperative recovery for children undergoing mini-middle-operations. Methods Thirty children undergoing mini-middle-operation were randomly divided into two groups: the propofol-ketamine group (15 cases), continuous infusion of propofol [4~6 mg/(kg·h) ] and ketamine [2~3 mg/(kg·h)]during the operation; the ketamine group (15 cases), intermittent intravenous injection of ketamine [1~2 mg/kg] during the operation. Results During the operation the function of circulation in the propofol-ketamine group was more steady than that in the ketamine group. The incidences of involuntary movement and nystagmus were less in the propofol-ketamine group than the ketamine group. The amount of ketamine was less and the time for recovery was shorter in the propofol-ketamine group than the ketamine group (P<0.05). Conclusion Compared with intravenous ketamine anesthesia, propofol-ketamine combined anesthesia is more steady and faster to awake after operation and therefore more suitable to children's operation.

关 键 词：异丙酚-氯胺酮 复合静脉麻醉 手术中 小儿 单纯氯胺酮麻醉 呼吸循环功能 持续静脉泵入 术后恢复时间 不自主运动 恢复情况 静脉注射 眼球震颤 手术麻醉 术后苏醒 小手术 混合液 显著性 

分 类 号：R647[医药卫生—外科学] R614.24[医药卫生—临床医学]