卵泡穿刺结合人工授精治疗多囊卵巢综合征不育  

Treatment of ovarian follicle puncture and artificial insemination in infertile women with polycystic ovary syndrome

作　　者：程丹[1] 杨菁[1] 徐望明[1] 龙文[1] 苏红[1] 

机构地区：[1]武汉大学人民医院生殖医学中心,湖北武汉430060

出　　处：《生殖医学杂志》2005年第3期148-150,共3页Journal of Reproductive Medicine

摘　　要：目的探讨一种有效治疗多囊卵巢综合征(PCOS)合并不育的方法。方法对12例PCOS患者15个周期采用促性腺激素刺激卵泡发育,配合经阴道B超下卵泡穿刺术释放卵母卵泡,再行人工授精。结果15个周期中妊娠4例,妊娠率为27%;治疗后第2次月经周期中1例自然妊娠,其他病例在3个月内月经恢复正常,但之后5例月经周期延长,2例复发闭经;患者血黄体生成素(LH)和睾酮(T)值治疗后明显低于治疗前(P<0.05)。结论卵泡穿刺结合人工授精,能迅速阻断PCOS的病理环节,具有创伤较小、疗效确切、简便等优点,可作为治疗PCOS不育的一种选择。Objective: To assess an effective method for treating polycystic ovary syndrome (PCOS) induced infertility.Methods: Fifteen cycles of 12 infertile patients with PCOS were performed with ovulation induction, follicle drilling and artificial insemination.Results: Four patients gained clinical pregnancy in the treatment cycle (including one pregnancy in the second cycle). The pregnancy rate was 27%. The others resumed a normal menstruation within 3 months, but 5 patients had oligomenorrhea and 2 amenorrhea thereafter. Blood LH and testosterone levels of the patients after ovarian follicle puncture treatment were lower than those before.Conclusion: The treatment can inhibit PCOS pathophysiological process. It is a simple, safe and effective method for treating PCOS induced infertility.

关 键 词：多囊卵巢综合征 卵泡 穿刺 人工授精 

分 类 号：R711.6[医药卫生—妇产科学]