硼污染的个人暴露剂量及其代谢的研究  

Individual exposure dosage of boron pollution and its metabolism.

作　　者：邢小茹[1] 魏复盛[2] 吴国平[2] 荀琳[3] Wendie A Robbins 王春利 魏春 姜欣 葛宏斌 

机构地区：[1]北京科技大学,北京100083 [2]中国环境监测总站,北京100029 [3]美国加州大学洛杉矶分校职业与环境健康中心 [4]丹东市环境监测站,辽宁丹东118002

出　　处：《中国环境科学》2005年第3期271-274,共4页China Environmental Science

基　　金：中美科技合作项目(1900-G-DC811)

摘　　要：以62名处于不同生活、工作环境下的人群为对象,研究了其通过空气粉尘、饭菜和饮水的日硼暴露剂量及通过尿液、粪便的代谢状况.结果表明,从事硼作业的53名工人日硼暴露均值11.8mg/d,是对照人群(1.52mg/d)的7.8倍;通过尿液代谢的硼占总代谢量的94%以上,且班后尿硼与24h全尿硼浓度的相关系数为0.952,班后尿样可代替全尿并反映硼的代谢水平;下班后尿硼浓度与日硼暴露剂量显著相关.多元线性回归可以反映不同暴露途径对尿硼水平的贡献,方程拟合度为43.0%,与实测值的平均相对偏差为23.6%.Daily exposure dosage of boron through air-dust, food and drinking water and through urine and excrement metabolism state were reported with the crowd of 62 persons under different living and working environment as research objects. The average daily exposure dosage of boron among 53 workers was 11.8 mg/d being 7.8 times of that among control group of 1.52 mg/d; the boron through urine metabolism was more than 94% of total amount of the metabolism; boron concentration of after-shift urine and that of 24 h urine were correlated with coefficient of 0.952; after-shift urine sample could stand for that of 24 h urine and reflect boron metabolism level; there was remarkable correlation between boron concentration of after-shift urine and daily exposure dosage of boron; multiple linear regressions could reflect more the contribution of different ways of exposure to the boron level in urine, with equation fitting rate of 43.0%. The average of relative deviation between the urine boron concentrations predicted with regression equation and actual the measured value was 23.6%.

关 键 词：硼污染 暴露剂量 尿硼浓度 代谢量 

分 类 号：R12[医药卫生—环境卫生学]