Synthesis of Novel Chitosan Microspheres Grafted with β-Cyclodextrins and Their Adsorption for Iodine for Antibacterial Activities  

作　　者：YIYing WANGYu-ting ZHANGXue-yong PANGZhi-yi PENGQi LIUHui 

机构地区：[1]CollegeofResourcesandEnvironmentalSciences,WuhanUniversity,Wuhan430072,Hubei,China

出　　处：《Wuhan University Journal of Natural Sciences》2005年第3期591-596,共6页武汉大学学报（自然科学英文版）

基　　金：SupportedbytheStateEducationalCommitteeDoctoral FoundationofChina(2000048615)

摘　　要：The novel chitosan microspheres grafted with beta-cyclodextrins (CMGC) wereprepared by means of the reaction of chitosan microspheres and mono-(6-p-tosyl)- beta-cyclodextrins(beta-CD-OTs-6). beta-CD-OTs-6 were gained by the reaction of p-toluenesul-fonyl chloride (TsCl) andbeta-cyclodextrins (beta-CDs). Their structures were proved by Fourier transform infrared spectralanalysis (FT-IR), X ray powder diffraction analysis, and ^(13)C NMR; the configuration of CMGC wascharacterized by scanning electron micrograph (SEM) and transmittance electron micrograph (TEM). Theinclusion complex of CMGC with iodine was prepared and its inclusion ability was studied. Theexperimental results showed that some iodine was included with CMGC and formed a stable inclusion.The stable complex of CMGC and iodine (CMGC-1) shows good antibacterial effect.The novel chitosan microspheres grafted with beta-cyclodextrins (CMGC) wereprepared by means of the reaction of chitosan microspheres and mono-(6-p-tosyl)- beta-cyclodextrins(beta-CD-OTs-6). beta-CD-OTs-6 were gained by the reaction of p-toluenesul-fonyl chloride (TsCl) andbeta-cyclodextrins (beta-CDs). Their structures were proved by Fourier transform infrared spectralanalysis (FT-IR), X ray powder diffraction analysis, and ^(13)C NMR; the configuration of CMGC wascharacterized by scanning electron micrograph (SEM) and transmittance electron micrograph (TEM). Theinclusion complex of CMGC with iodine was prepared and its inclusion ability was studied. Theexperimental results showed that some iodine was included with CMGC and formed a stable inclusion.The stable complex of CMGC and iodine (CMGC-1) shows good antibacterial effect.

关 键 词：BETA-CYCLODEXTRIN chitosan microspheres IODINE ANTI-BACTERIA 

分 类 号：O636.1[理学—高分子化学]