多层螺旋CT肾脏灌注成像的实验研究  

Renal perfusion imaging with multi-slice spiral CT: an experimental study

作　　者：孙建男[1] 郭启勇[1] 杨立国[2] 幺刚[2] 房津辉[2] 岳泉[2] 

机构地区：[1]中国医科大学附属第二医院放射科,辽宁沈阳110004 [2]大庆油田总医院CT室,黑龙江大庆163001

出　　处：《中国医学影像技术》2005年第6期831-833,共3页Chinese Journal of Medical Imaging Technology

摘　　要：目的　探讨多层螺旋CT灌注扫描在肾脏血流灌注中的应用及对比剂注射流率对灌注参数的影响。方法　健康家兔36只随机分成A、B、C三组,对比剂量为2 ml/kg(300 mgI/ml),注射流率三组分别为1 ml/s,2 ml/s,3 ml/s。对肾脏灌注扫描后获得的灌注参数进行定量分析。结果　A组和B组之间,B组和C组之间各项灌注参数无显著差异(P>0.05);A组和C组之间各项灌注参数有显著差异(P<0.05)。肾脏皮质和髓质的灌注参数明显不同(P<0.05)。结论　多层螺旋CT可对肾脏组织血流灌注进行定量分析,但注射流率影响灌注数值。Objective To evaluate the application of multi-slice spiral CT perfusion imaging in the kidney and the influence of various injection rate on perfusion parameters. Methods Thirty-six health rabbits were randomly divided into three groups (A, B, C), the dose of contrast agent were 2 ml/kg (300 mgI/ml ), the injection flow rate in each group were 1ml/s, 2ml/s, and 3ml/s respectively to make a quantitative analysis for the parameter of renal perfusion imaging. Results Every perfusion parameter was no significant difference not only between group A and group B, but also between group B and group C (P> 0.05 ), but there was a significant difference between group A and group C (P<0.05). Perfusion parameters were significant difference in cortex and medulla of the same kidney (P<0.05). Conclusion Multi-slice spiral CT can provide quantitative analysis to renal blood perfusion, but injection flow rate influence the perfusion parameters.

关 键 词：体层摄影术 x线计算机 灌注 肾 兔 

分 类 号：R814.42[医药卫生—影像医学与核医学] Q9533[医药卫生—放射医学]