多层螺旋CT回顾性心电门控技术检测冠状动脉钙化斑块不同重建方法的比较和优化选择  

Optimization and comparison of different reconstruction methods of retrospectively ECG-gated multislice CT for coronary artery calcium plaques

作　　者：王颖[1] 赵虹[1] 韩铭钧[1] 柳学国[1] 何艳丽[1] 刘晓彬[1] 

机构地区：[1]中山大学附属第五医院放射科,广东珠海519000

出　　处：《中国医学影像技术》2005年第6期877-880,共4页Chinese Journal of Medical Imaging Technology

基　　金：珠海市科学技术局基金资助(PC20041038)

摘　　要：目的　评价多层螺旋CT采用回顾性心电门控技术不同重建方法对冠状动脉钙化斑块检出及钙化积分的影响。方法　对55例疑诊冠心病患者采用16层螺旋CT扫描回顾性心电门控技术行冠状动脉钙化积分检查,每一病例原始数据进行三组不同层厚(2 mm、3 mm和5 mm),层间隔分别重叠50%重建。计算每组图像钙化斑块的Agatston积分(AS ),容积积分(VS),质量积分(MS),比较三种重建方法在冠状动脉钙化斑块检出及计算钙化积分的差别。结果　2 mm层厚组检出的钙化斑块最多为234个,其中小钙化斑块为185 个;与2 mm组比较,3 mm组与5 mm组检出全部钙化的敏感性分别为84%、62%;小钙化斑块的敏感性为83%、54%。全部钙化斑块及小钙化斑块的钙化积分VS、MS、AS以2 mm组最高,其次为3 mm组,最低为5 mm组;钙化积分三组间比较以及每两组间比较均有明显差异性(P<0.05)。结论　在探测冠状动脉钙化灶应采用薄层重叠重建。2 mm层厚的图像能显示更多、更小的钙化斑块,对于临床冠状动脉钙化斑块的确定及冠心病风险预测有重要意义。Objective To evaluate the effects of multislice CT detecting and quantify coronary artery calcium plaques with different reconstruction methods of retrospectively ECG-gated multislice CT, and to choose the optimal reconstruction method for coronary artery calcium. Methods Fifty-five patients underwent coronary artery calcium (CAC) studies with retrospectively ECG-gated multislice CT. Each patient's data was reconstructed with three different slice thickness (2, 3 and 5 mm) and increment overlapping by 50%. The volume score (VS), mass score (MS) and agatston score (AS) were measured and compared. Results The number to detect all calcium plaques were 234 and small calcium plaques were 185 in images with 2 mm slice thickness; Compared with 2 mm slice thickness images, the sensitivity to detect all calcium plaques and small calcium plaques were 84%, 62% and 83%, 54% in images with 3 mm, 5 mm slice thickness respectively. There was a smaller value in VS, MS and AS in 5 mm group than 2 mm and 3 mm group (P<0.05), and 3 mm group than 2 mm group (P<0.05). Conclusion Thinner slice imaging with overlapping reconstruction methods should be used in detecting and quantifying coronary artery calcium plaques. 2 mm images can detect more and smaller calcium plaques. It is essential to detect coronary artery calcium plaques and predict coronary events in clinical practice.

关 键 词：冠状动脉 钙化 体层摄影术 X线计算机 

分 类 号：R543.3[医药卫生—心血管疾病] R814.42[医药卫生—内科学]