一种新型的显微镜载玻片自动装载系统设计  

Design of a Novel Automated Slide-loader System for Optical Microscope

作　　者：张宏波[1] 曾立波[1] 许贤泽[1] 柯亨玉[1] 龚丹[1] 张云飞[2] 

机构地区：[1]武汉大学电子信息学院,湖北武汉430072 [2]解放军信息工程大学测绘学院,河南郑州450052

出　　处：《应用基础与工程科学学报》2005年第2期185-193,共9页Journal of Basic Science and Engineering

基　　金："十五"国家科技攻关重大项目(项目编号:2001BA210A02

摘　　要：提出了一种新型的显微镜载玻片自动装载系统的实现方案,着重论述了该系统的机械结构、装载和卸载逻辑、控制器的硬件结构和软件设计.该系统机械部分由载玻片盒、特制的载物台和机械臂组成,这三者的顺序动作实现了载玻片在载玻片盒和样品夹之间的装载和卸载.控制器通过USB总线接收计算机发出的运动指令,并产生变频信号源来驱动载玻片盒、载物台和机械臂在其各自运动轴方向上的运动.实验结果表明,该系统完成一次载玻片的加载、卸载过程需要分别占用15s和9s,载玻片在样品夹内X、Y轴方向上重复定位误差分别为±7.6μm和±5.2μm.将其与显微图像处理软件相结合,能实现一次25个分析样品的批处理工作,大大提高了显微镜的工作效率.A novel automated slide-loader system for optical microscope is presented. The mechanism structure, the control logic for the slide loading and unloading procedure, the hardware construction and software design of the control box are discussed. This slide-loader mechanism comprises a slide cassette, a custom-built stage and a slide exchange arm to automatically transfer a slide from the cassette to the stage and then return the slide back into the cassette. The control box receives movement instructions from the computer via USB, and produces frequency-changeable signal sources to drive the cassette, the stage and the arm orderly. Experiments show that the slide loading and unloading process need 15 s and 9 s respectively, and the reorientation accuracy of slide in the sample clip is 7.6 μm in X direction and 5.2 μm in Y direction. Combining this slide-loader system with sophisticated image processing software available, twenty-five slides covered by certain sample can be auto-analyzed in batches, greatly promoting the efficiency of optical microscopes.

关 键 词：载玻片 显微镜 系统设计 自动装载系统 图像处理软件 USB总线 实现方案 机械结构 机械部分 软件设计 硬件结构 顺序动作 卸载过程 重复定位 分析样品 工作效率 控制器 机械臂 载物台 片盒 计算机 信号源 批处理 运动 指令 

分 类 号：TP317.4[自动化与计算机技术—计算机软件与理论] TS871.1[自动化与计算机技术—计算机科学与技术]