脑健冲剂对AD大鼠5-HT和MAO影响的实验研究  

The experiment study of naojian inhalant effection on 5-HT and MAO of AD rat

作　　者：李霄凌[1] 周忠光[2] 王志国[2] 

机构地区：[1]齐齐哈尔医学院解剖教研室,黑龙江齐齐哈尔161000 [2]黑龙江中医药大学,黑龙江哈尔滨150040

出　　处：《中医药学报》2005年第3期46-47,i001,共3页Acta Chinese Medicine and Pharmacology

摘　　要：目的采用脑健冲剂治疗AD,观察脑健冲剂对AD大鼠海马区5-羟色胺和MAO的影响。方法本实验采用D-半乳糖拟衰老,Aβ1-40损害联合所致AD模型,用脑健冲剂治疗。结果脑健冲剂可提高海马5-羟色胺含量和降低MAO的水平。结论脑健冲剂可治疗AD。Objective:we use the naojian inhalant to treat AD and study its effection on 5-HT and MAO of hippocampus CA1 region of AD rat.Methods:The experiment used D-semilactose and the Aβ_~1-40 emergency aged as model animals,and used naojian inhalant to treat AD.Results:the naojian inhalant can increase 5-HT and reduce MAO.Conclusions:which indicates that Naojian inhalant has important effection to AD rats.

关 键 词：阿尔茨海默病 脑健冲剂 5-羟色胺 单胺氧化酶 β-淀粉样蛋白(Aβ) 

分 类 号：R285.5[医药卫生—中药学]