大肠杆菌热敏性肠毒素研究进展  

Advance of Studying Heat-labile Enterotoxin of Escherichia coli

作　　者：庄娟[1] 曹祥荣[2] 潘洁[1] 饶忠[1] 陈波[1] 尤永进[1] 

机构地区：[1]上海市农业科学院畜牧兽医研究所,上海201106 [2]南京师范大学生命科学学院,南京210097

出　　处：《上海农业学报》2005年第2期108-111,共4页Acta Agriculturae Shanghai

摘　　要：大肠杆菌肠毒素是引起腹泻的主要致病因子,可以分为热敏性肠毒素和耐热性肠毒素两类。本文就热敏性肠毒素的理化性质、分子结构和生物学功能、免疫原性、免疫佐剂作用以及国内外对其免疫原性与佐剂效应的应用研究进行了综述。The enterotoxins produced by E.coli are the main diarrhea-causing pathogenic factor, and they fall into two groups: heat-labile toxin and heat-stable toxin. This paper reviews the physicochemical properties, molecular structure, biological functions, and immunogenicity of heat-labile enterotoxin as well as the applied research of immunoadjuvant effects at home and abroad.

关 键 词：热敏性肠毒素 分子结构 生物学功能 免疫原性 免疫佐剂 大肠杆菌 腹泻 

分 类 号：S852.612[农业科学—基础兽医学] R378.21[农业科学—兽医学]