检测神经性毒剂生物传感器的研究  

Study of biosensor for detecting nerve agents

作　　者：施云波[1] 彭忠明[2] 张洪泉 董新平[1] 郭建英[1] 

机构地区：[1]哈尔滨理工大学测量技术与通讯工程学院 [2]中国工程物理研究院结构力学研究所,四川绵阳621900

出　　处：《传感器技术》2005年第5期22-24,共3页Journal of Transducer Technology

基　　金：黑龙江省科技攻关项目(GC03A121);国家自然科学基金资助项目(60272002)

摘　　要：阐述了通过微结构设计实现电化学技术与生物酶技术的有机结合,制造出对神经性毒剂敏感的生物传感器,分析了传感器的工艺制造过程,解决了酶的选择、酶的提纯、酶的固定化、底液、电极制作等关键技术。讨论了传感器的性能特点,稳定工作时间大于8h,传感器响应时间小于10min,零点漂移小于±2VDC。A method of realizing the adequate integration of electrochemistry technology and biologic enzyme technology using a microstructure design methodology is presented,and a type of biosensor that is sensitive to nerve agents is developed.Analyzing the process of technology and manufacture of the biosensor solves the pivotal technologies such as the enzyme’s selection,the enzyme’s purification,the enzyme’s solidification,basic liquid,the electrode’s facture,etc.The characteristic of the above presented biosensor is discussed.The biosensor property is stable,working time is ≥8h,its response time is less than 10min,and its zero shift,±2VDC.

关 键 词：神经毒剂 生物传感器 酶 电化学 

分 类 号：TP212[自动化与计算机技术—检测技术与自动化装置]