高效液相色谱法测定强阳灵口服液中淫羊藿苷的含量  

Determination of icariin in Qiangyangling oral liquids by HPLC

作　　者：宋福坤 赵勤[2] 

机构地区：[1]苏州市第二人民医院,江苏苏州215002 [2]苏州市药品检验所,江苏苏州215002

出　　处：《中国现代应用药学》2005年第3期254-255,共2页Chinese Journal of Modern Applied Pharmacy

摘　　要：目的建立高效液相色谱法测定强阳灵口服液中淫羊藿苷含量的方法。方法采用HPLC法,在波长284mm以乙腈水(23∶77)为流动相,测定淫羊藿苷的含量。结果淫羊藿苷在0.241～1.203μg范围内呈良好线性关系(r=0.9995)平均回收率为99.0%(RSD=1.0%,n=5)。测定5批样品的RSD为0.5～0.9%。结论所建立的方法可准确进行定量检测,可用于该制剂的质量控制。OBJECTIVE To develop a HPLC method for determination of icariin Qiangyangling oral liquids.METHODS The method was performed on VP-BDS column,acetonitrile-water(23∶77)was used as mobile phase,the detection wavelength was 284nm.RESULTS The assay was linear over the range of 0.24 1~1.203μg, r =0.9995.The average recovery was 99.0%,with the RSD=1.0%.CONCLUSION The method developed is accurate,sensitive and repeatable.It can be applied to the quality control of Qiangyangling oral liquids.

关 键 词：强阳灵口服液 淫羊藿苷 高效液相色谱法 含量测定 

分 类 号：R917.792[医药卫生—药物分析学]