^（99m）Tc－MIBI心肌显像中肺摄取增高及其意义的探讨  

Significance of Increased Lung ￣(99m)Tc-MIBI Uptake During Myocardial Imaging

作　　者：张永学[1] 曾腊玲[1] 高再荣[1] 袁斌[1] 胡佳[1] 安锐[1] 

机构地区：[1]同济医科大学附属协和医院核医学科

出　　处：《中国医学影像学杂志》1995年第3期185-187,共3页Chinese Journal of Medical Imaging

摘　　要：本文从未经处理的心肌断层前位图像上测定了３５例正常人和１３０例心脏病患者的肺／心比值。结果表明，正常人运动心肌显像肺／左室心肌（Ｌ／ＬＶ）比值为０．３５３±０．０４７。以均值＋２Ｓ作为正常值上限时，心肌缺血和高血压病组分别有２４％和２０％的患者Ｌ／ＬＶ增高。心肌梗塞组，静息显像有５１．９％的患者Ｌ／ＬＶ增高。Ｌ／ＬＶ与ＬＶＥＦ之间呈负相关（ｒ＝－０．６１５，ｐ＜０．００１），Ｌ／ＬＶ增高者的ＬＶＥＦ明显低于比值正常者，提示测定肺部^（９９ｍ）Ｔｃ－ＭＩＢＩ的摄取可提供心功能障碍及其程度的资料。A lung/ heart ratio of ￣(99m)Tc-MIBI uptake was measured from an anterior image of the unprocessed myocardial tomographic image in 35 normal and 130 heart diseases patients. The lung/left ventricle(L/LV) ratios of normal subjects were 0.353±0.047 in exercise images. When the mean +2SD of ratios derived from 35 normal subjects was considered as the normal upper limit, a increased lung-to-heart ratio was found in 24% myocardial ischemia and 20% hypertension patients. However, 14 of 27(51.9%)patients with myocardial infarctions showed an increased ratio at rest. On the other hand, there was a significantly negative(r=-0.6 15,P<0.001) correlation between L/LV ratio and LVEF. LVEF was significantly lower (P<0.01) in subjects with an increased ratio than in those with a normal ratio. Thus the measurement of￣(99m)Tc-MIBI lung / heart ratios may provide information regarding the severity of cardiac dysfunction.

关 键 词：心肌 肺 放射性核素成像 锝 诊断应用 心脏病 

分 类 号：R541[医药卫生—心血管疾病]