大剂量多巴酚丁胺数字式超声心动图诊断冠心病的评价  

High-dose Dobutamine Digital Echocardiography for Detecting Coronary Artery Disease

作　　者：孙铁军[1] 马彩娥[1] 纪秀梅 高习文[1] 周乃胜[1] 范国华[1] 

机构地区：[1]青岛海军401医院

出　　处：《中国医学影像学杂志》1994年第3期152-154,共3页Chinese Journal of Medical Imaging

摘　　要：报告了大剂量多巴酚丁胺数字式超声心动图诊断冠心病的方法。试验中发现室壁节段性运动异常是诊断心肌缺血的较早、敏感和特异的指标，而心率是多巴酚丁胺造成心肌缺血的最重要的生理性决定因素。受试者５０人，其中病例组３０人（劳力型心绞痛２０例，急性心肌梗塞１０例），对照组２０人。总敏感性８０％，特异性９０％，诊断准确率８４％。本试验有助于检出无心电图表现的胸痛缺血或无痛性心肌缺血的冠心病患者。This study assessed the value of high-dose dobutamine digital echocardiography (DBADE)for detecting coronary artery disease (CAD ). We found that a new segmental ventricular wall motion abnormality induced by dobutamine was an early,sensitive and specific index for detecting myocardial ischemia. Heart rate was the most important physiologic determinent of ischemia induced by dobutamine. 50 men were studied, including 30 cases of CAD(20 cases of stenocardia, 10 of acute myocardial infarction) and 20 normal persons. The overall sensitivity was 80%,specificity 90% and accuracy 84%. It was helpful to detect the myocardial ischemia without any variation in ECG or any angina pectoris.

关 键 词：大剂量 多巴酚丁胺 数字式超声心动图 诊断 冠心病 

分 类 号：R541.4[医药卫生—心血管疾病] R445.12[医药卫生—内科学]