模拟失重条件下与听觉方位区分关联的脑电位变化  

Changes of Brain Potentials Related to Auditory Location Discrimination during Simulated Weightlessness

作　　者：赵仑[1] 魏金河[1] 任维[1] 

机构地区：[1]航天医学工程研究所,北京100094

出　　处：《航天医学与医学工程》2001年第2期97-101,共5页Space Medicine & Medical Engineering

摘　　要：目的探明模拟失重条件下听觉方位区分的脑反应特性 ,进一步了解模拟失重条件下脑功能的变化特点。方法 1 4名右利手正常被试者以头低位倾斜 ( - 1 0° ,HDT)模拟失重 ,头高位倾斜 ( + 1 0°,HUT)为对照。要求被试者对声音信号进行音调选择方位区分。结果靶和非靶信号均产生了明显的事件相关电位 (ERPs) ;与HUT相比 ,HDT条件下ERPs的变化表现为慢电位的负向偏移 ;ERPs的变化有一定的方位和脑区特征 ,即以右后方位的T ERPs受影响最大 ,右前方位受影响最小 ,且T和NT ERPs均以F5 区受影响最大。结论HDT对听觉方位区分时脑功能状态有一定的影响。Objective To study changes of brain response in distinguishing auditory location during simulated weightlessness. Method The event related potentials (ERPs) during auditory location discrimination were compared between head down tilt (HDT) and head up tilt (HUT) conditions among 14 healthy subjects. Result (1)Both the target (T) and non target (NT) auditory signals induced significant ERPs; (2)The slow potential was significantly lower for both T and NT ERPs during HDT as compared with that during HUT; (3)The reduction of mean slow potential amplitude during HDT was more significant for the target signals from right rear position and lightest for the target signals from right front position.This phenomenon was more remarkable at left front area. Conclusion These data provide further evidence that the higher brain function was affected by simulated weightlessness.

关 键 词：失重模拟 听觉 方位区分 事件关联电位 脑电图 

分 类 号：R852.22[医药卫生—航空、航天与航海医学]