色素绒毛结节性滑膜炎28例报道  

Pigmented Villonodular Synovitis:a report of 28 Cases

作　　者：王荣茂[1] 王和鸣[1] 严孟宁[1] 余英豪[2] 李廷泰[1] 

机构地区：[1]福建省人民医院骨科,福州市350004 [2]南京军区福州总医院

出　　处：《罕少疾病杂志》2000年第3期11-13,共3页Journal of Rare and Uncommon Diseases

摘　　要：目的 探讨色素绒毛结节性滑膜炎 (PVS)的临床病理特点、治疗和预后的关系。方法 本组 PVS28例，男 13例，女 15例，年龄 12～ 53岁。膝关节 15例，手指 7例，足背 4例，颞颌及骶髂关节各 1例，多肢体 1例。局限型 19例，弥漫型 9例。伴外伤史 3例，骨破坏 4例，恶变 2例，半月板破裂 1例，滑膜血管瘤 1例。均行滑膜切除，早期操练， 3例加放疗。 28例均经病理证实。结果 22例随访 2～ 18年， 13例功能良好； 9例复发者 5例功能欠佳， 2例截指 (趾 )， 2例死亡。放疗者 3例均复发。结论 PVS临床病理均有肿瘤的特征，可恶变和转移，易复发，最佳治疗是彻底的滑膜切除而不是放疗。Objective To study the clinical and pathologic characteristics,relationship between the treatment and the prognosis of pigmented villonodular synovitis (PVS).Methods 28 cases of PVS were reviewed, including 15 knees,7 fingers,4 feet,1 temporamandibular joint,1 sacroiliac joint and 1 multiple focuses, 13 cases of male and 15 of female, ranged from 12～ 53 years old, 19 localized and 9 diffused. 3 cases were associated with injury history, 4 with bone destruction， 2 with malignant change and 1 with synovial hemangioma .All cases were resected and early manipulated. Radiotherapy was added to 3 cases. All were confirmed by pathology.Results 22 cases were followed up 2～ 18 years. The results of 13 cases were good and 9 who had a recurrence were poor including 1 toe and 1 finger amputated,2 cases died. Radiotherapy could not hinder recurrence. Conclusion PVS tends to show some characteristics of tumor, may be malignant and appears metastasis.The best treatment was thorough synovectomy than radiotherapy.

关 键 词：色素绒毛结节性滑膜炎 滑膜切除 

分 类 号：R686.7[医药卫生—骨科学]