血浆纤维结合蛋白在评价半饥饿大鼠营养状况中的意义  

Application of plasma fibronectin in nutritional assessment in semistarved rats

作　　者：郭长江[1] 韦京豫[1] 杨继军[1] 葛玉章[1] 陈西京[1] 徐琪寿 

机构地区：[1]天津卫生学环境医学研究所,300050 [2]天津放射医学研究所,300050

出　　处：《中国临床营养杂志》1999年第1期18-20,共3页Chinese Journal of Clinical Nutrition

摘　　要：为了探讨血浆纤维结合蛋白在营养状况评价中的意义，本研究采用半饥饿大鼠模型，观察了血浆纤维结合蛋白以及其它血浆蛋白水平的动态变化。结果显示实验四周内，半饥饿可引起血浆纤维结合蛋白、前白蛋白、白蛋白水平的显著下降，其中血浆前白蛋白的变化最为灵敏。提示半饥饿可以引起血浆纤维结合蛋白显著下降，但是其变化没有血浆前白蛋白灵敏。结合以往的研究结果，就影响血浆纤维结合蛋白变化的因素及其作为营养状况评价指标意义进行讨论。In order to evaluate plasma fibronectin as a marker in nutritional assessment, changes in plasma fibronectin as well as other plasma proteins concentrations were investigatal in semistarved rats in this study. The results showed that plasma fibronectin, prealbumin and albumin concentrations decreased significantly during 4 wk semi-starvation.However, plasma prealbumin behaved more senstive than plasma fibronection. The possible facors responsible for plasma fibronectin conentration changes and its significane in nutritional essessment are discussed in theis paper.

关 键 词：血浆纤维结合蛋白 半饥饿 营养状况评价 前白蛋白 蛋白水平 大鼠模型 动态变化 评价指标 蛋白变化 下降 灵敏 

分 类 号：R722.13[医药卫生—儿科] R151.2[医药卫生—临床医学]