眼镜蛇毒对微循环和血液流变性的影响  

Effects of Venom of Naja Naja Atra on Microcirculation and Hemorrheology

作　　者：罗健东[1] 赵延德[1] 管锦霞[1] 郑有顺[2] 

机构地区：[1]广州医学院药理教研室 [2]第一军医大学

出　　处：《微循环学杂志》1992年第3期11-13,共3页Chinese Journal of Microcirculation

摘　　要：静脉注射眼镜蛇毒(0.15mg/kg)或组份Ⅸ—Ⅰ(0.075mg/kg)能使大白鼠肠系膜细动静脉扩张,颈动脉血压下降,血流速度减慢,持续时间10min,随后血流速度加快。并能使兔的全血粘度和血浆粘度降低,纤维蛋白原减少。The venom of naja naja atra (VNNA 0. 15mg/kg) and fraction Ⅸ—Ⅰ(0. 075mg/kg) (ⅳ) were able to be mesenteric arteriole and venule of rat dilating, cervical arterial pressure falling and blood flow velocity quicken. VNNA and fraction Ⅸ—Ⅰ were able to reduce viscosity of whole blood and plasma and fibrinogen in rabbits.

关 键 词：眼镜蛇毒 血液流变性 微循环 血流速度 纤维蛋白原 静脉扩张 静脉注射 血压下降 血浆粘度 全血粘度 肠系膜 大白鼠 颈动脉 

分 类 号：R996.3[医药卫生—毒理学] R285.5[医药卫生—药学]