精氨酸强化肠外营养对外科危重病人免疫功能影响的研究  

Effects of arginine enriched parenteral nutrition on immune function of critical patients

作　　者：赵铁军[1] 王贵和[1] 

机构地区：[1]安徽省铜陵市人民医院普外Ⅱ科,244000

出　　处：《中国临床营养杂志》2000年第3期170-171,共2页Chinese Journal of Clinical Nutrition

摘　　要：目的　观察精氨酸强化肠外营养对术后外科危重病人免疫功能的影响。　方法　选择危重病人 30例 ,随机分为实验组采用精氨酸强化肠外营养和对照组应用常规的肠外营养。营养支持前后分别检验T细胞亚群 (CD3+、CD4 +、CD8+) ,NK细胞活性 ,IL 2受体浓度。　结果　营养支持后 9天实验组CD4 +、CD4 +/CD8+、NK细胞活性、IL 2受体浓度较营养支持前明显升高 ,统计学差异显著 ,而对照组所有指标改善无明显统计学意义。　结论　精氨酸强化肠外营养可以改善外科危重病人的免疫功能。Objectives In order to study the effects of arginine enriched PN on immune function of critical patients after operation. Methods Tirty patients were randomly divided into experimental group, in which patients received PN enriched with arginine, and control group (PN), T lym phocyete Subsets (CD 3 +、CD 4 +、CD 8 +),natural killer (NK) Cell activity and IL 2 level were calculated before and after PN. Results In experimental group, there were significant improvements on CD 4 +、CD 4 +/CD 8 +、NK cell activity IL 2 on the nineth day after PN, but, there weren't significant difference in control group. Conclusion TPN enriched with arginine could improve the immune function in critical patients.

关 键 词：外科危重病人 精氨酸强化 肠外营养 免疫功能 影响的研究 NK细胞活性 IL-2受体 CD4^+ 营养支持 T细胞亚群 方法选择 差异显著 对照组 实验组 统计学 浓度 

分 类 号：R459.3[医药卫生—治疗学]