新生儿濒死状态的血糖水平变化及其临床意义  

The Change of Blood Glucose Level in Dying Neonates and its Clinical Significance

作　　者：詹晓斌[1] 

机构地区：[1]苏州大学附属儿童医院新生儿科,苏州215003

出　　处：《苏州医学院学报》2000年第10期906-907,共2页Acta Academiae Medicinae Suzhou

摘　　要：目的　观察新生儿濒死病例的血糖水平变化 ,探讨其临床意义。方法　使用Novastatprofile - 5型血气、电解质分析仪检测血浆葡萄糖浓度 ,将同组患儿入院当时首次血糖及同期同条件痊愈患儿作为对照组观察。结果　死亡组濒死血糖浓度 (12 .49± 6 .49mmol/L)显著高于入院后首次血糖浓度 (8.0 8± 4.82mmol/L) (P <0 .0 5 ) ;对照组出院前末次血糖浓度 (4 .5 1± 1.85mmol/L)与入院当时首次血糖浓度 (4 .6 2± 1.2 3mmol/L)无显著差异 (P >0 .0 1) ;死亡与对照两组 ,入院首次血糖浓度间差别显著 (P <0 .0 5 ) ;死亡组濒死血糖浓度与对照组出院前末次血糖浓度差别高度显著 (P <0 .0 1) ;提示病情越严重血糖水平越高。Objective To estimate blood glucose level of dying neonates in our department and its clinical singnificance.Methods Nova Stat Profile-5 style blood electrolyte analysis instrument was used to test the glucose level in plasma.The blood glucose level of the children patients measured at the time of admission and that of the children patients who were admitted in the same period and were cured perfectly under the same conditions were taken as controls.Results The blood glucose level in the death group just before their dying was 12.49±6.49mmol/L,the blood glucose in the death group measured at the time of admission was 8.08±4.82mmol/L,the blood glucose level in the control group just before its discharge was 4.51±1.85mmol/L,the blood glucose level in the control group at the time of admission was 4.61±1.23mmol/L.The blood level in the death group just before their dying was higher than the level at the time of admission ( P <0.05),and was higher than the level in the control group just before their discharge ( P <0.01).The blood level of control group at the time of admission and that just before their discharge had no significant diference ( P >0.1),the blood glucose level in death group just at the time of admission was higher than that in the control group ( P < 0.05 ).Through these number,we were able to find that the blood level in the dying neonates was higher than when they just were admitted in the hospital,and was also higher than that in the control group,so that it reveded the blood glucose level will be higher when the situation became more serious.Couclusion The change of blood glucose level in neonates may be one of the indications of disease situation's change.

关 键 词：临床意义 水平变化 新生儿 濒死状态 血糖浓度 葡萄糖浓度 分析仪检测 对照组 NOVA stat 血糖水平 病情变化 死亡组 出院前 电解质 入院后 患儿 差别 

分 类 号：R512.6[医药卫生—内科学] R722.12[医药卫生—临床医学]