美沙酮替代递减法用于海洛因依赖者戒毒治疗的评估性研究  

CLINICAL STUDY FOR ASSESSING THE TREATMENT OF HEROIN ADDICTS BY METHADONE SUBSTITUTION METHOD WITH DIFFERENT DOSING SCHEDULES

作　　者：万文鹏 李建华 张锐敏 冯再坤 杨桂英 杨茂彬 朱华 

机构地区：[1]昆明药物依赖性治疗康复中心,昆明650031

出　　处：《中国药物依赖性通报》1993年第1期19-24,共6页

摘　　要：本文对海洛因成瘾者用美沙酮进行戒毒的不同治疗方案进行评估。A组53例采用18-21 d给药的经验方案;B组69例采用14 d个体化给药方案。结果表明,美沙酮两种给药方案均有肯定的戒毒效果。B组的戒断症状较轻,波动小,症状控制及治疗时间均优于A组。A study for evaluating the treatment of heroin addicts by different dosing schedules of methadone substitution methods was undertaken. Group A (53 clients) was treated with regular 18-21 d dosing schedule. Group B (69 clients) was treated by 14 d individualized dosing schedule. Results showed that both dosing schedules were effective. The abstinence syndromes of Group B were less severe than those of group A and the fluctuation of syndromes was less evident. It is concluded that the dosing schedule of methadone in Group B is better than Group A.

关 键 词：海洛因依赖者 美沙酮 替代递减法 戒毒治疗 个体化给药方案 海洛因成瘾者 治疗方案 戒毒效果 戒断症状 治疗时间 症状控制 经验方 B组 

分 类 号：R595.5[医药卫生—内科学] R972[医药卫生—临床医学]