备用根大鼠脊髓后角组织提取液对培养的鸡胚背根节神经突起生长的影响  

Influence of the Extracts from Spinal Dorsal Horn of Rat with Spared Root on Neurite Outgrowth of Dorsal Root Ganglion of Chick Embryo in Vitro

作　　者：章尧[1] 曾园山[1] 郭畹华[1] 罗超权[1] 

机构地区：[1]中山医科大学神经科学研究室生物化学教研室

出　　处：《解剖科学进展》1997年第1期87-90,共4页Progress of Anatomical Sciences

基　　金：国家自然科学基金

摘　　要：应用组织培养方法，观察备用根大鼠手术侧和非手术侧脊髓后角组织提取液对鸡胚背根节神经突起生长的影响。结果显示：备用根大鼠手术侧脊髓后角组织提取液作用的背根节神经突起生长密度（１５５．２５±１４．２５）明显高于非手术侧提取液作用的背根节神经突起生长密度（８９．１４±９．６０）。提示部份去传入纤维支配的脊髓后角组织可能存在着促进神经突起生长的神经营养活性物质。The influence of the extracts from operated side and unoperated side spinal dorsal horn of rat with spared root on neurite outgrowth of dorsal root ganglion (DRG) of chick embryo was observed by tissue cultural method. The result showed that DRG neurite density treated by the extract from operated side spinal dorsal horn was obvious more than that from unoperated side. It indicated that the extract from spinal dorsal horn with partial deafferentation may contain a kind of neurotrophic active substance promoting neurite outgrowth.

关 键 词：备用根模型 大鼠 脊髓后角 组织提取液 鸡胚 背根节 神经突起 神经纤维 

分 类 号：R322.8[医药卫生—人体解剖和组织胚胎学]