癌胚抗原和糖类抗原测定在胸水诊断中的价值  

The Diagnosis Value of Determination of Carcinoembryonic Antigen(CEA) and Carbohydrate Antigen(CA) in Patients with Hydrothorax

作　　者：吴苏武[1] 卢东生[1] 余天峰[1] 

机构地区：[1]广东省汕头市中心医院内六科,广东汕头515031

出　　处：《河北医学》2005年第7期632-634,共3页Hebei Medicine

摘　　要：目的:探讨测定血清和胸水中糖类抗原(CA153、CA199、CA125)、癌胚抗原(CEA)对鉴别良恶性胸水的价值。方法:采用放射免疫分析法,测定良恶性胸水患者的血清和胸水CA153、CA199、CA125、CEA进行比较。结果:恶性胸水患者的血清和胸水中CA153、CA199、CEA均高于良性胸水[差异有极显著性(P<0.01)],血清CA125在良性组和恶性组差异无显著性,而胸水CA125在两组中差异有极显著性(P<0.01)。结论:联合检测CEA和糖类抗原有助于提高良恶性胸水的鉴别诊断。Objective: To explore the value of determinating Carcinoembryonic Antigen(CEA) and Carbohydrate Antigen(CA153,CA199,CA125) in serum and hydrothorax in differentiation of benign and malignant hydrothorax . Method: Carcinoembryonic Antigen(CEA) and Carbohydrate Antigen(CA153,CA199,CA125) in serum and hydrothorax of both benign and malignant cases were measured. Result: CA153,CA199 and CEA of malignant cases in serum and hydrothorax were higher than those of benign cases(P<0.01). CA125 in serum of both benign and malignant cases had no statistical differences,but that in hydrothorax had statistical differences(P<0.01). Conclusion: Combined determination of Carcinoembryonic Antigen(CEA) and Carbohydrate Antigen(CA153,CA199,CA125) can improve the differentiate diagnosis of benign and malignant hydrothorax.

关 键 词：抗原测定 价值 癌胚抗原(CEA) CA199 良恶性胸水 放射免疫分析法 血清CA125 CA153 糖类抗原 显著性 良性胸水 鉴别诊断 联合检测 患者 

分 类 号：R817.4[医药卫生—影像医学与核医学]