单次大剂量丙种球蛋白静脉注射治疗新生儿ABO溶血病疗效观察  

Therapeutic effect of intravenous injection of gammaglobulin by single high-dose on neonatal ABO hemolytic disease

作　　者：利丹 郭伟中 

机构地区：[1]广东省韶关市第一人民医院儿科,512000

出　　处：《河北医药》2005年第5期342-343,共2页Hebei Medical Journal

摘　　要：目的观察单次大剂量静脉注射丙种球蛋白(IVIG)治疗新生儿ABO溶血病的疗效。方法将30例新生儿ABO溶血病随机分为两组,在常规光疗基础上,治疗组给予IVIG1g/kg静脉滴注,一次治疗;观察组给予IVIG500mg·kg-1·d-1静脉滴注,连用3d。结果治疗组黄疸消退时间明显缩短(P<0.05)。结论单次大剂量静脉注射丙种球蛋白治疗新生儿ABO溶血病是一种有效而又经济的疗法。Objective To observe the therapeutic effect of intravenous injection of gammaglobulin by single high-dose on neonatal ABO hemolytic disease.Methods 30 patients with ABO hemolytic disease were divided into two groups,trial group and control group.The patients in trial group were treated with IVIG (1 g/kg,iv gtt,1 d),and the patients in control group were treated with IVIG (500 mg·kg -1 ·d -1 ,iv gtt,3 d).Results The time of jaundice extinction in trial group was obviously shorter than that in control group ( P <0.05).Conclusion The therapy of intravenous injection of gammaglobulin by single high-dose is an effective and economic methodl in the treatment of neonatal ABO hemolytic disease.

关 键 词：大剂量 丙种球蛋白 静脉注射 治疗 新生儿 ABO溶血病 疗效观察 

分 类 号：R722.18[医药卫生—儿科]