丙交酯的合成与聚合  

Synthesis and polymerization of lactide for biomedical materials

作　　者：朱久进[1] 王远亮[1] 

机构地区：[1]重庆大学生物工程学院生物力学与组织工程教育部重点实验室,重庆400044

出　　处：《化工新型材料》2005年第4期20-21,19,共3页New Chemical Materials

基　　金：国家自然科学基金(30270395)

摘　　要：丙交酯是由乳酸合成聚乳酸的中间体,采用新型La Ti复合氧化物催化乳酸合成丙交酯,粗丙交酯经乙酸乙酯纯化后,差热分析仪测得其熔点为126 4℃,纯化后的丙交酯在一定条件下,经辛酸亚锡引发,开环聚合成聚乳酸,并用红外光谱和差热分析仪对聚乳酸进行了表征。Lactide is intermediate for the preparation of PLA from lactic acid.La-Ti compound oxide catalyst was employed to prepare lactide from lactic acid, the crude lactide was recrystallised with ethyl acetate, melting point was 126.4℃ determined by the DSC method. Under suitable reaction conditions,the lactide intermediate was ring-opening polymerrzed to PLA initiating by tin di-(2-ethyl-hexanoate). The polymer was characterized by IR and DSC.

关 键 词：丙交酯 合成 差热分析仪 聚合 复合氧化物 聚乳酸 乙酸乙酯 辛酸亚锡 红外光谱 中间体 纯化 

分 类 号：TQ316.33[化学工程—高聚物工业]