中药克敏抗过敏作用的实验研究  

Experimental Study on Anti-anaphylaxis Function of Kemin

作　　者：刘文泰[1] 李丽华[1] 王文智[1] 

机构地区：[1]河北医科大学,石家庄050091

出　　处：《河北中医药学报》2005年第2期21-22,共2页Journal of Hebei Traditional Chinese Medicine and Pharmacology

基　　金：石家庄市科技局重点科研资助课题:98262045

摘　　要：目的研究纯中药制剂克敏的抗过敏作用。方法运用Schultzdale反应试验。结果克敏原液、0.3倍稀释液及3倍浓缩液均能显著抑制卵蛋白致敏豚鼠离体回肠肌的过敏性收缩反应(P<0.01),并呈明显剂量依赖性。结论克敏能显著的抗I型超敏反应。Objective: to study the anti-anaphylaxis function of Kemin, a pure Chinese drug prepn Methods: it was tested by means of Schultz-dale reaction Results: stock solution of Kemin, dilution by 03 times and concentrated solution by3 times could inhibit significantly the anaphylactic contractile response of ex vivo ileum muscle in cavia cobaya with anaphylaxis by egg albumin (p<001), and present significant dose dependence Conclusion: Kemin can react significantly to anti- hypersensitivity of type I

关 键 词：中药 抗过敏 Schultz-dale反应 抗Ⅰ型超敏反应 

分 类 号：R285.6[医药卫生—中药学]