双歧杆菌口服液对肝硬化上消化道出血后感染的影响  

Effect of Bifidobacterium Oral Liquid on Infection after Hemorrhage of Upper Digestive Tract due to Hepatocirrhosis

作　　者：于培龙 刘朝阳[1] 

机构地区：[1]安阳市第五人民医院,河南安阳455000

出　　处：《实用中医药杂志》2005年第7期391-392,共2页Journal of Practical Traditional Chinese Medicine

摘　　要：目的:了解双歧杆菌口服液对肝硬化上消化道出血后感染及预后的影响。方法:观察组35例在综合治疗基础上加用双歧杆菌口服液,对照组36例只给予综合治疗,两组均不用抗感染药物。结果:观察组与对照组感染发生率分别为34.3%、58.3%,肝性脑病发生率分别为8.6%、27.8%,临床死亡率分别为5.7%、22.2%,两组比较均有显著性差异(P<0.05)。结论:肝硬化上消化道出血用双歧杆菌调节肠道菌群、抑制肠道中革兰氏阴性杆菌的生长及移位、发挥生物拮抗作用以减少内毒素及氨的产生和吸收,可减少感染及肝性脑病的发生,有效降低死亡率。Objective:To find out the effect of Bifidobacterium Oral Liquid on infection after hemorrhage of upper digestive tract due to hepatocirrhosis and the prognosis.Method:35 cases were added Bifidobacterium Oral Liquid based on complex treatment as the study group while 36 cases were only received complex treatment as the control group.Neither of the two groups was treated with anti-infection medicine.Result:The infection rate of the study group and the control group is separately 34.3% and 58.3%.The originating rate of hepatic encephalopathy is separately 8.6% and 27.8%.The death rate in clinic is separately 5.7% and 22.2%.There are great differences in two groups (P<0.05).Conclusion:Bifidobacterium used in hemorrhage of upper digestive tract due to hepatocirrhosis has the function of accommodating intestinal flora,inhibiting the growth and movement of gram-negative bacilli in intestine,playing biological antagonistic action to decrease the production and absorbability of endotoxin and ammonia.Therefore,it can reduce infection and hepatic encephalopathy,and decreace the death rate effectively.

关 键 词：肝硬化 上消化道出血 双歧杆菌口服液 感染 

分 类 号：R259.752[医药卫生—中西医结合]