淋巴细胞中钙信号的研究进展  

Progress in Ca^(2+) signal of lymphocytes

作　　者：柴迎梅[1] 黄晓航[2] 刘晨临[2] 丛柏林[2] 刘胜浩[2] 李光友[2] 

机构地区：[1]中国海洋大学生命学院海洋生物系,山东青岛266003 [2]国家海洋局第一海洋研究所,山东青岛266061

出　　处：《免疫学杂志》2005年第B06期50-53,共4页Immunological Journal

摘　　要：钙信号是细胞中普遍存在的第二信使。几乎所有的细胞程序都直接或间接地受细胞内钙信号的影响。对于细胞内钙离子浓度的调节是许多生物体系所采用的最一般的信号机制。淋巴细胞中的钙信号在调控淋巴细胞的功能中起关键作用,淋巴细胞的激活、增殖以及功能的发挥都依靠钙信号的传导。本文综述了淋巴细胞中钙信号的功能和分子调控机制研究的最新进展。Ca2+ stgnal is a common signaling mechanism existed in the cells. Practically every cellular process is directly or indirectly influenced hy changes in intracellular Ca2+ signal. The modulation of intracellular Ca2+ concentration is a common signaling mechanism used in many biological systems. Ca2+ signal of lymphocytes is crucial for the function of lymphocytes. Lymphocytes rely on Ca + signaling to initiate activation, proliferation, and functional activity. The recent research progress in the function and molecular mechanism of Ca2+ signal in lymphocytes are summarized in this paper.

关 键 词：钙信号 淋巴细胞 分子机制 

分 类 号：Q25[生物学—细胞生物学]